Endothelin B Receptor antibody

Sheep anti Rat endothelin B receptor antibody (AAR43) is suitable for use in immunocytochemistry on acetone fixed cells.
Product Details
- Target Species
- Rat
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Human - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to rat ET-B (CT) was raised by repeated immunisation of sheep with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Keyhole limpet haemocyanin (KLH) conjugated C-terminal peptide KANDHGYDNFRSSNN corresponding to amino acids 424 to 437 of rat endothelin B receptor.
- Approx. Protein Concentrations
- IgG concentration 1.41mg/ml
Storage Information
- Storage
- Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P21451
- P24530
- P48302
- Entrez Gene
- Ednrb
- EDNRB
- Ednrb
- GO Terms
- GO:0005886 plasma membrane
- GO:0001600 endothelin-B receptor activity
- GO:0001934 positive regulation of protein phosphorylation
- GO:0016021 integral to membrane
- GO:0005624 membrane fraction
- GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
- GO:0007204 elevation of cytosolic calcium ion concentration
- GO:0008217 regulation of blood pressure
- GO:0030318 melanocyte differentiation
- GO:0031702 type 1 angiotensin receptor binding
- GO:0031965 nuclear membrane
- GO:0042310 vasoconstriction
- GO:0042311 vasodilation
- GO:0043066 negative regulation of apoptosis
- GO:0048265 response to pain
- GO:0048484 enteric nervous system development
- GO:0050678 regulation of epithelial cell proliferation
- GO:0051930 regulation of sensory perception of pain
- GO:0005515 protein binding
- GO:0001755 neural crest cell migration
- GO:0006885 regulation of pH
- GO:0007422 peripheral nervous system development
- GO:0007497 posterior midgut development
- GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0014043 negative regulation of neuron maturation
- Regulatory
- For research purposes only
Applications of Endothelin B Receptor antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunocytochemistry | |||
Immunofluorescence | 10 | 20ug/ml | |
Immunohistology - Paraffin | 10 | 20ug/ml | |
Immunoprecipitation | 20 | 40ug/ml |
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Rabbit anti Sheep IgG (H/L):Biotin | 5184-2304 | C E F WB | 1.5 ml |
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Donkey anti Sheep/Goat IgG:DyLight®488 | STAR88D488GA | F IF | 0.1 mg |
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Donkey anti Sheep/Goat IgG:FITC | STAR88F | C | 1 mg |
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Donkey anti Sheep/Goat IgG:HRP | STAR88P | C E P WB | 1 ml |
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Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Antigen Retrieval Buffer, pH8.0 | BUF025A | P | 500 ml | ||
Antigen Retrieval Buffer, pH8.0 | BUF025C | P | 50 ml |
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