TDP-43 antibody
Mutations in the TPD43 gene are implicated in development of Amyotrophic lateral sclerosis 10, a neurodegenerative disorder affecting motor neurons leading to eventual fatal paralysis (Van Deerlin et al. 2008).
Goat anti Human TDP-43 antibody recognizes human TDP-43 as a single band of ~45kDa in multiple cell line lysates by western blotting under reducing conditions. The antibody also cross-reacts with rodent cell line lysates tested.
Product Details
- Target Species
- Human
- Western Blotting
- Anti TDP-43 antibody detects a band of approximately 45 kDa in NIH/3T3 cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Goat polyclonal antibody purified by ammonium sulfate precipitation followed by antigen affinity chromatography
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin - Immunogen
- Peptide sequence C-HISNAEPKHNSNRQ from an internal region of TDP-43
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q13148
- Entrez Gene
- TARDBP
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of TDP-43 antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Donkey anti Sheep/Goat IgG:HRP | STAR88P | C E P WB | 1 ml |
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