MTHFD1L is involved in the synthesis of tetrahydrofolate (THF) in mitochondria. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for MTHFD1L (provided by RefSeq, Jun 2011).
Goat anti Human MTHFD1L antibody detects a band of 105 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti MTHFD1L detects a band of approximately 105 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse Rat
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Goat polyclonal antibody purified by affinity chromatography
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3) 0.5% BSA
- Peptide with the sequence C-DTNDRFLRKITIGQ, from the internal region of the protein sequence
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- As supplied, 12 months from date of despatch.
- Entrez Gene
- GO Terms
- GO:0005739 mitochondrion
- GO:0004329 formate-tetrahydrofolate ligase activity
- GO:0005524 ATP binding
- GO:0006730 one-carbon metabolic process
- GO:0009396 folic acid-containing compound biosynthetic process
- GO:0015942 formate metabolic process
- GO:0042803 protein homodimerization activity
- GO:0046653 tetrahydrofolate metabolic process
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of MTHFD1L antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Donkey anti Sheep/Goat IgG:HRP||STAR88P||C E P WB||1 ml|