Carbonic Anhydrase II antibody

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Sheep anti Carbonic Anhydrase II

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00073
Datasheet
WB
MSDS
100 µl

Sheep anti Human carbonic anhydrase II antibody recognizes carbonic anhydrase II (CA-II), also known as carbonate dehydratase II and carbonic anhydrase C (CAC). CA-II is a ubiquitous zinc enzyme that catalyzes the reversible conversion of carbonic acid (H2CO3) to carbon dioxide (CO2) and water (H2O). Carbonic anhydrase inhibitors have now been a mainstay of human clinical intervention for several decades, with at least 25 clinically used drugs that are CA inhibitors

Sheep anti Human carbonic anhydrase II antibody detects a single band of 29 kDa in the human epidermoid carcinoma A431 cell line lysate. Cross reactivity with mouse cell lines is also seen.

Product Details

Target Species
Human
Western Blotting
Sheep anti carbonic anhydrase II detects a band of approximately 29 kDa in A431 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Sheep polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
P00918
Entrez Gene
CA2
GO Terms
GO:0004089 carbonate dehydratase activity
GO:0006730 one-carbon metabolic process
GO:0008270 zinc ion binding
GO:0045177 apical part of cell
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Carbonic Anhydrase II antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Rabbit anti Sheep IgG (H/L):HRP 5184-2504 C E WB 2 mg loader