alpha-Lactalbumin antibody

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Sheep anti Human Lactalbumin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
5602-5008 E 1 ml
Sheep anti Human lactalbumin antibody detects human alpha-lactalbumin, a small Ca2+ binding protein, the predominant protein found in human milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase complex, with beta 1,4-galactosyltransferase forming the catalytic component. Lactose synthase catalyzes and regulates the biosynthesis of lactose in the lactating mammary gland.

A folding variant of alpha-lactalbumin called HAMLET (human alpha-lactalbumin made lethal to tumor cells), has been shown to selectively kill tumor cells and control tumor progression in vivo.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Bovine Weak
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Serum - liquid
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Lactalbumin from human milk

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P00709 Related reagents
Entrez Gene
LALBA Related reagents
GO Terms
GO:0005509 calcium ion binding
GO:0042742 defense response to bacterium
GO:0004461 lactose synthase activity
GO:0007165 signal transduction
GO:0005615 extracellular space
GO:0005989 lactose biosynthetic process
GO:0006917 induction of apoptosis
GO:0007267 cell-cell signaling
Regulatory
For research purposes only

Applications of alpha-Lactalbumin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit anti Sheep IgG (H/L):Biotin 5184-2304 1.5 ml C E F WB
Donkey anti Sheep/Goat IgG:DyLight®488 STAR88D488GA 0.1 mg F IF
Donkey anti Sheep/Goat IgG:DyLight®549 STAR88D549GA 0.1 mg F IF
Donkey anti Sheep/Goat IgG:DyLight®649 STAR88D649GA 0.1 mg F IF
Donkey anti Sheep/Goat IgG:FITC STAR88F 1 mg C
Donkey anti Sheep/Goat IgG:HRP STAR88P 1 ml C E P WB

Product Specific References

References for alpha-Lactalbumin antibody

  1. Gustafsson, L. et al. (2005) HAMLET kills tumor cells by apoptosis: structure, cellular mechanisms, and therapy.
    J Nutr. 135 (5): 1299-303.