Sheep anti cyclic GMP antibody recognizes cyclic guanosine monophosphate (cGMP) a secong messenger molecule similar to cAMP. cGMP is synthesized from GTP under the influence of soluble guanylate synthase. cGMP then activates protein kinases to mediate cellular processes including vasodilation or transcription factor activation.
- Target Species
- Product Form
- Serum - liquid
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Succinylated cGMP conjugated to BSA.
- Store at +4°C. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
- 18 months from date of despatch.
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Cyclic GMP antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
Product Specific References
References for Cyclic GMP antibody
Mátyás C et al. (2015) The soluble guanylate cyclase activator cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus.
Cardiovasc Diabetol. 14 (1): 145.