Tpa antibody | D12-9A7
Mouse anti Human Tpa:Biotin
- Product Type
- Monoclonal Antibody
- Clone
- D12-9A7
- Isotype
- IgG1
- Specificity
- Tpa
| Mouse anti Human tPA antibody, clone D12-9A7, recognizes tissue type plasminogen activator (tPA) also known as PLAT. tPA is a serine protease that in the intravascular space, catalyzes the conversion of plasminogen to plasmin. tPA is expressed in various cell types including endothelial cells, glial cells and neurons. Within the brain tPA plays a role in synaptic plasticity, detection and adaptation to metabolic stress, modulation of the blood-brain barrier permeability and remodeling of the extracellular matrix (Jeanneret & Yepes 2017). The biotinylated Mouse anti Human tPA antibody, clone D12-9A7 (MCA6283B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human tPA antibody, clone D11-7G8 (MCA6282GA) as the capture antibody. |
- Target Species
- Human
- Product Form
- Purified IgG conjugated to Biotin - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin - Immunogen
- Purified native human tPA
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- ELISA Matched Pair(s)
-
ELISA Matched Pair-Capture Antibody:
MCA6282GA
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human Tpa | MCA6282GA | E | 0.1 mg |
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| List Price | Your Price | ||||||
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| Description | Mouse anti Human Tpa | ||||||
MCA6283B
100005528
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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