Tpa antibody | D12-9A7

Mouse anti Human Tpa:Biotin

Product Type
Monoclonal Antibody
Clone
D12-9A7
Isotype
IgG1
Specificity
Tpa

Product Code Applications Pack Size List Price Your Price Qty
MCA6283B
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SDS Safety Datasheet SDS
E 0.1 mg loader
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Mouse anti Human tPA antibody, clone D12-9A7, recognizes tissue type plasminogen activator (tPA) also known as PLAT. tPA is a serine protease that in the intravascular space, catalyzes the conversion of plasminogen to plasmin. tPA is expressed in various cell types including endothelial cells, glial cells and neurons. Within the brain tPA plays a role in synaptic plasticity, detection and adaptation to metabolic stress, modulation of the blood-brain barrier permeability and remodeling of the extracellular matrix (Jeanneret & Yepes 2017).

The biotinylated Mouse anti Human tPA antibody, clone D12-9A7 (MCA6283B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human tPA antibody, clone D11-7G8 (MCA6282GA) as the capture antibody.

Target Species
Human
Product Form
Purified IgG conjugated to Biotin - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Immunogen
Purified native human tPA
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml
Fusion Partners
Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
ELISA Matched Pair(s)
ELISA Matched Pair-Capture Antibody: MCA6282GA
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Mouse anti Human Tpa MCA6282GA E 0.1 mg loader
List Price Your Price
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Description Mouse anti Human Tpa

UniProt
P00750
Entrez Gene
PLAT
View more products with Tpa specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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