TCR Alpha/Beta antibody | IP26
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Mouse anti Human TCR alpha/ beta antibody, clone IP26 recognizes a constant region determinant found on the surface of all alpha/beta TCR bearing T lymphocytes. Approximately 92% of all CD3 + peripheral blood lymphocytes are reactive.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
- Preparation
- Purified IgG prepared by affinity chromatography
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
0.09% Sodium Azide 0.2% Bovine Serum Albumin
Storage Information
- Storage
- Store at +4oC.
DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.
More Information
- UniProt
- P01850
- P01848
- Entrez Gene
- TRAC
- TRBC1
- GO Terms
- GO:0004872 receptor activity
- GO:0042605 peptide antigen binding
- GO:0005887 integral to plasma membrane
- GO:0006968 cellular defense response
- GO:0031295 T cell costimulation
- GO:0042287 MHC protein binding
- GO:0050852 T cell receptor signaling pathway
- GO:0005886 plasma membrane
- GO:0005515 protein binding
- GO:0016021 integral to membrane
- GO:0006955 immune response
- Regulatory
- For research purposes only
Applications of TCR Alpha/Beta antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Flow Cytometry | Neat |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 5ul of the suggested working dilution to label 5 x 105 cells in 100ul.
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Negative Isotype Controls Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Mouse IgG1 Negative Control:FITC | MCA928F | F | 100 Tests |
|
Useful Reagents Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Human Seroblock | BUF070A | F | 50 Test | ||
| Human Seroblock | BUF070B | F | 200 Test |
Product Specific References
References for TCR Alpha/Beta antibody
-
Sullivan, B.M. & Coscoy, L. (2008) Downregulation of the T-cell receptor complex and impairment of T-cell activation by human herpesvirus 6 u24 protein.
J Virol. 82 (2): 602-8. -
Nataj Arab, H.H. et al. (2015) Phenotypical characterization of the peripheral blood T cells in patients with celiac disease: does it differentiate suspicious celiac disease cases?
Gastroenterol Hepatol Bed Bench. 8 (2): 132-9. -
Liao, Z. et al. (2017) A Local Inflammatory Renin-Angiotensin System Drives Sensory Axon Sprouting in Provoked Vestibulodynia.
J Pain. Jan 3. pii: S1526-5900(16)30367-4. [Epub ahead of print]
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