CCL14 antibody | B02-1G7

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Mouse anti Human CCL14:Biotin

Product Type
Monoclonal Antibody
Clone
B02-1G7
Isotype
IgG1
Product Code Applications Pack Size List Price Quantity
MCA6179B
Datasheet
E
SDS
0.1 mg loader

Mouse anti Human CCL14 antibody, clone B02-1G7, recognizes C-C motif chemokine 14, also known as HCC1 and NCC-2. CCL14 is a CC-type chemokine which is constitutively expressed in many tissues (Gu et al. 2020), and present at very high concentrations in normal human plasma (Savino et al. 2009). This chemokine is involved with activation of immune cells, promoting chemotaxis of monocytes, eosinophils, and T lymphoblasts. CCL14 is involved with pathogenesis of allergic airway inflammation and some cancers. It has been identified as a prognostic biomarker in hepatocellular carcinoma, where it modules the cell cycle and promotes apoptosis (Zhu et al. 2019).

The biotinylated Mouse anti Human CCL14 antibody, clone B02-1G7 (MCA6179B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL14 antibody, clone B12-1D8 (MCA6178GA) as the capture antibody.

Product Details

Target Species
Human
Product Form
Purified IgG conjugated to Biotin - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Immunogen
E. coli derived recombinant human CCL14 (Thr20-Asn93)
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml
Fusion Partners
Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch

More Information

UniProt
Q16627
Entrez Gene
CCL14
GO Terms
GO:0004871 signal transducer activity
GO:0005615 extracellular space
GO:0006874 cellular calcium ion homeostasis
GO:0006955 immune response
GO:0008009 chemokine activity
GO:0008284 positive regulation of cell proliferation
Regulatory
For research purposes only

Applications of CCL14 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Useful Reagents Available

Description Product Code Applications Pack Size List Price Quantity
Mouse anti Human CCL14 MCA6178GA E 0.1 mg loader

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