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CCL14 antibody | B12-1D8

Mouse anti Human CCL14

Product Type
Monoclonal Antibody
Clone
B12-1D8
Isotype
IgG1
Specificity
CCL14

Product Code Applications Pack Size List Price Your Price Qty
MCA6178GA
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 0.1 mg loader
List Price Your Price
loader

Mouse anti Human CCL14 antibody, clone B12-1D8, recognizes C-C motif chemokine 14, also known as HCC1 and NCC-2. CCL14 is a CC-type chemokine which is constitutively expressed in many tissues (Gu et al. 2020), and present at very high concentrations in normal human plasma (Savino et al. 2009). This chemokine is involved with activation of immune cells, promoting chemotaxis of monocytes, eosinophils, and T lymphoblasts. CCL14 is involved with pathogenesis of allergic airway inflammation and some cancers. It has been identified as a prognostic biomarker in hepatocellular carcinoma, where it modules the cell cycle and promotes apoptosis (Zhu et al. 2019).

This purified Mouse anti Human CCL14 antibody, clone B12-1D8 (MCA6178GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human CCL14 antibody, clone B02-1G7 (MCA6179B) as the detection antibody.

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Carrier Free
Yes
Immunogen
E. coli derived recombinant human CCL14 (Thr20-Asn93)
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Fusion Partners
Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Description Product Code Applications Pack Size List Price Your Price Quantity
Mouse anti Human CCL14:Biotin MCA6179B E 0.1 mg loader
List Price Your Price
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Description Mouse anti Human CCL14:Biotin

UniProt
Q16627
Entrez Gene
CCL14
GO Terms
GO:0004871 signal transducer activity
GO:0005615 extracellular space
GO:0006874 cellular calcium ion homeostasis
GO:0006955 immune response
GO:0008009 chemokine activity
GO:0008284 positive regulation of cell proliferation

MCA6178GA

100005288

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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