D-Dimer

Native Human D-Dimer

Product Type
Purified Protein
Specificity
D-Dimer

Product Code Applications Pack Size List Price Your Price Qty
4440-0256
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SDS Safety Datasheet SDS
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Human D-dimer (DD) is a specific degradation product of cross-linked fibrin. It can be used as a marker of venous thromboembolism for the diagnosis of deep venous thrombosis of the lower limbs and pulmonary embolism.

Target Species
Human
Product Form
Purified protein from human plasma - liquid
Preparation
Streptokinase lysis of coagulated fibrinogen, gel filtered on Sephadex G-150.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
None present
Purity
SDS PAGE: >90%
Approx. Protein Concentrations
Total protein concentration 1.0mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

References for D-Dimer

  1. Ibupoto, Z.H. et al. (2014) The Development of Highly Sensitive and Selective Immunosensor Based on Antibody Immobilized ZnO Nanorods for the Detection of D-Dimer
    Electroanalysis. 26 (2): 292-8.
  2. Georgia-Paraskevi, N. et al. (2014) A Selective Immunosensor for D-dimer Based on Antibody Immobilized on a Graphene Electrode with Incorporated Lipid Films
    Electroanalysis. 26 (7): 1522-7.

UniProt
P02671
P02675
P02679
Entrez Gene
FGA
FGB
FGG
GO Terms
GO:0002576 platelet degranulation
GO:0030674 protein binding, bridging
GO:0005102 receptor binding
GO:0007165 signal transduction
GO:0005577 fibrinogen complex
GO:0009897 external side of plasma membrane
GO:0030168 platelet activation
GO:0031093 platelet alpha granule lumen
GO:0043499 eukaryotic cell surface binding
GO:0051258 protein polymerization
GO:0051592 response to calcium ion
GO:0051087 chaperone binding
GO:0005625 soluble fraction
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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