C-Reactive Protein

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Native Human C-Reactive Protein

Product Type: Purified Protein

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
1707-2029 Datasheet	E SDS	1 mg	Log in		Get Quote

Human C-reactive protein is a sterile filtered preparation derived from pleural ascites. C-reactive protein is an acute phase protein produced by the liver, a marker of inflammation and useful for monitoring and predicting coronary artery disease.

Product Details

Target Species: Human
Product Form: Purified C-reactive Protein - liquid
Preparation: Purified protein prepared by affinity chromatography on CH-Sepharose and hydroxylapatite
Buffer Solution: TRIS buffered saline
Preservative Stabilisers: 0.1% Sodium Azide (NaN₃)
Purity: >98% by SDS PAGE
Approx. Protein Concentrations: Total protein concentration 1.0 mg/ml
Protein Molecular Weight: May exist as a 140 kDa pentamer under native conditions or as a 26 kDa monomer under reduced conditions

Storage Information

Storage: Store at +4^oC. DO NOT FREEZE.
This product should be stored undiluted.
Guarantee: Guaranteed until date of expiry. Please see product label.

More Information

UniProt: P02741
Entrez Gene: CRP
GO Terms: GO:0005515 protein binding; GO:0006953 acute-phase response; GO:0046872 metal ion binding; GO:0008228 opsonization; GO:0010745 negative regulation of macrophage derived foam cell differentiation; GO:0010888 negative regulation of lipid storage; GO:0030169 low-density lipoprotein particle binding; GO:0033265 choline binding; GO:0051637 Gram-positive bacterial cell surface binding
Regulatory: For research purposes only

Applications of C-Reactive Protein

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
ELISA

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Product Specific References

References for C-Reactive Protein

Tomita, S. et al. (2016) Artificial Modification of an Enzyme for Construction of Cross-Reactive Polyion Complexes To Fingerprint Signatures of Proteins and Mammalian Cells.
Anal Chem. 88 (18): 9079-86.
Zheng,Y. & DemarcoM. (2017) Manipulating trypsin digestion conditions to accelerate proteolysis and simplify digestion workflows in development of protein mass spectrometric assays for the clinical laboratory
Clinical Mass Spectrometry. [Epub ahead of print].

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