C-Reactive Protein

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Native Human C-Reactive Protein

Product Type
Purified Protein
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
1707-2029 E 1 mg
Human C-reactive protein is a sterile filtered preparation derived from pleural ascites. C-reactive protein is an acute phase protein produced by the liver, a marker of inflammation and useful for monitoring and predicting coronary artery disease.

Product Details

Target Species
Human
Product Form
Purified C-reactive Protein - liquid
Preparation
Purified protein prepared by affinity chromatography on CH-Sepharose and hydroxylapatite
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
Purity
>98% by SDS PAGE
Approx. Protein Concentrations
Total protein concentration 1.0 mg/ml
Molecular Weight
1707-2029 may exist as a 140 kDa pentamer under native conditions or as a 26 kDa monomer under reduced conditions.

Storage Information

Storage
Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted.
Shelf Life
Please see label for expiry date.

More Information

UniProt
P02741 Related reagents
Entrez Gene
CRP Related reagents
GO Terms
GO:0005515 protein binding
GO:0006953 acute-phase response
GO:0046872 metal ion binding
GO:0008228 opsonization
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010888 negative regulation of lipid storage
GO:0030169 low-density lipoprotein particle binding
GO:0033265 choline binding
GO:0051637 Gram-positive bacterial cell surface binding
Regulatory
For research purposes only

Applications of C-Reactive Protein

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Product Specific References

References for C-Reactive Protein

  1. Tomita, S. et al. (2016) Artificial Modification of an Enzyme for Construction of Cross-Reactive Polyion Complexes To Fingerprint Signatures of Proteins and Mammalian Cells.
    Anal Chem. 88 (18): 9079-86.
  2. Zheng,Y. & DemarcoM. (2017) Manipulating trypsin digestion conditions to accelerate proteolysis and simplify digestion workflows in development of protein mass spectrometric assays for the clinical laboratory
    Clinical Mass Spectrometry. [Epub ahead of print].