Human C-reactive protein is a sterile filtered preparation derived from pleural ascites. C-reactive protein is an acute phase protein produced by the liver, a marker of inflammation and useful for monitoring and predicting coronary artery disease.
- Target Species
- Product Form
- Purified C-reactive Protein - liquid
- Purified protein prepared by affinity chromatography on CH-Sepharose and hydroxylapatite
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- >98% by SDS PAGE
- Approx. Protein Concentrations
- Total protein concentration 1.0 mg/ml
- Protein Molecular Weight
- May exist as a 140 kDa pentamer under native conditions or as a 26 kDa monomer under reduced conditions
- Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted.
- Guaranteed until date of expiry. Please see product label.
- Entrez Gene
- GO Terms
metal ion binding
negative regulation of macrophage derived foam cell differentiation
negative regulation of lipid storage
low-density lipoprotein particle binding
Gram-positive bacterial cell surface binding
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of C-Reactive Protein
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for C-Reactive Protein
Tomita, S. et al. (2016) Artificial Modification of an Enzyme for Construction of Cross-Reactive Polyion Complexes To Fingerprint Signatures of Proteins and Mammalian Cells.
Anal Chem. 88 (18): 9079-86.
Zheng,Y. & DemarcoM. (2017) Manipulating trypsin digestion conditions to accelerate proteolysis and simplify digestion workflows in development of protein mass spectrometric assays for the clinical laboratory
Clinical Mass Spectrometry. [Epub ahead of print].