Recombinant chicken interferon alpha is the immunogen used to produce the polyclonal Rabbit anti Chicken interferon alpha antibody.
- Target Species
- Product Form
- Purified recombinant protein expressed in E.coli - liquid.
- Recombinant protein prepared from E.coli
- Buffer Solution
- 0.05M Sodium Acetate
1M Sodium Chloride
- Preservative Stabilisers
- None present
- >85% by Ni chelate chromatography
- Approx. Protein Concentrations
- Total protein concentration 1.0 mg/ml
- Protein Molecular Weight
- 19 kD
- Store at -20oC only.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein.
This product should be stored undiluted.
Should this product contain a precipitate we recommend microcentrifugation before use.
- 3 months from date of despatch
- Entrez Gene
- GO Terms
- GO:0006952 defense response
- GO:0009615 response to virus
- GO:0005125 cytokine activity
- GO:0005126 cytokine receptor binding
- GO:0005615 extracellular space
- For research purposes only
Applications of IFN Alpha
|Application Name||Verified||Min Dilution||Max Dilution|
Product Specific References
References for IFN Alpha
Schultz, U. et al. (1995) Recombinant chicken interferon: a potent antiviral agent that lacks intrinsic macrophage activating factor activity.
Eur J Immunol. 25 (3): 847-51.
Plachy, J. et al. (1999) Protective effects of Type I and Type II interferons toward Rous Sarcoma Virus-induced tumors in chickens.
Virology. 256: 85-91.
Schwarz, H. et al. (2004) Synthesis of IFN-beta by virus-infected chicken embryo cells demonstrated with specific antisera and a new bioassay.
J Interferon Cytokine Res. 24 (3): 179-84.
Schultz, U. et al. (1995) Recombinant chicken interferon from Escherichia coli and transfected COS cells is biologically active.
Eur J Biochem. 229 (1): 73-6.
Jiang, H. et al. (2011) Chicken interferon alpha pretreatment reduces virus replication of pandemic H1N1 and H5N9 avian influenza viruses in lung cell cultures from different avian species.
Virol J. 8: 447.
Smith, S.E. et al. (2013) Chicken interferon-inducible transmembrane protein 3 restricts influenza viruses and lyssa viruses in vitro.
J Virol. 87 (23): 12957-66.
Alamares, J.G. et al. (2010) The interferon antagonistic activities of the V proteins from two strains of Newcastle disease virus correlate with their known virulence properties.
Virus Res. 147 (1): 153-7.
Lostalé-seijo, I. et al. (2016) Interferon induction by avian reovirus.
Virology. 487: 104-11.
Lostalé-seijo, I. et al. (2016) Response of Three Different Viruses to Interferon Priming and Dithiothreitol Treatment of Avian Cells.
J Virol. 90 (18): 8328-40.
Deng, L. et al. (2016) Characterization and functional studies of fowl adenovirus 9 dUTPase.
Virology. 497: 251-61.