PTK6 antibody
Rabbit anti PTK6
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- PTK6
Antibody Quality and Performance Guarantee
| Rabbit anti PTK6 antibody recognizes protein-tyrosine kinase 6, also known as breast tumor kinase and tyrosine-protein kinase BRK. PTK6 is a nonreceptor tyrosine kinase that is evolutionarily related to the FRK family of kinases and more distantly to the SRC family of tyrosine kinases (Qui and Miller 2002, Brauer and Tyner 2010). It controls various signaling pathways involved in the differentiation and maintenance of normal epithelia (Brauer and Tyner 2010). PTK6 substrates include AKT (Zhang et al. 2005), SLM1 and SLM2 (Haegebarth et al. 2004), STAT3 (Liu et al. 2006), STAT5b (Weaver and Silva 2007). PTK6 is coamplified and coexpressed with ErbB2 in human breast cancers to promote proliferation (Xiang et al. 2008). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to PTK6 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 222-451 of human PTK6
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/500 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti PTK6 antibody detects a band of approximately 60 kDa in various cell and tissue lysates under reducing conditions
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB * | 0.5 ml |
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| List Price | Your Price | ||||||
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| Description | TidyBlot Western Blot Detection Reagent:HRP | ||||||
- UniProt
- Q13882
- Entrez Gene
- PTK6
- GO Terms
- GO:0004715 non-membrane spanning protein tyrosine kinase activity
- GO:0005524 ATP binding
- GO:0005634 nucleus
- GO:0005737 cytoplasm
- GO:0006468 protein phosphorylation
AHP2725
156863
158907
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Request a different product with this specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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