Borrelia burgdorferi antibody
Rabbit anti Borrelia burgdorferi antibody (1439-9406) used for the detection of B. burgdorferi in canine myocardium by immunohistochemistry on formalin fixed, paraffin embedded tissue sections.
Image caption:
Microscopic examination of heart specimens. A- degeneration of myocardium with disturbances in cardiomyocyte structure, presence of fibrous tissue and mild inflammatory infiltrates (arrows) (H&E; 200x); B-severe cardiomyocyte degeneration accompanied by severe granulocytic and slight lymph o-plasmocytic infiltration in heart tissue adjutant to embolic material (H&E; 200x); C-severe granulocytic and moderate lympho-plasmocytic infiltration of infarct site (H&E; 200x); D-vegetative and spore forms of Borrelia burgdorferi in heart specimens (IHC stain, 600x); E-Borrelia burgdorferi spore forms in heart specimens (IHC stain, 600x).
From: Janus, I. et al. Myocarditis in dogs: etiology, clinical and histopathological features. 11 cases (2007-2013).
Irish Vet J. 2010 67:28.
This image is from an open access article distributed under the terms of the Creative Commons Attribution License.
Rabbit anti Borrelia burgdorferi antibody (1439-9406) used for the detection of B. burgdorferi in canine myocardium by immunohistochemistry on formalin fixed, paraffin embedded tissue sections.
Image caption:
Microscopic examination of heart specimens. A- degeneration of myocardium with disturbances in cardiomyocyte structure, presence of fibrous tissue and mild inflammatory infiltrates (arrows) (H&E; 200x); B-severe cardiomyocyte degeneration accompanied by severe granulocytic and slight lymph o-plasmocytic infiltration in heart tissue adjutant to embolic material (H&E; 200x); C-severe granulocytic and moderate lympho-plasmocytic infiltration of infarct site (H&E; 200x); D-vegetative and spore forms of Borrelia burgdorferi in heart specimens (IHC stain, 600x); E-Borrelia burgdorferi spore forms in heart specimens (IHC stain, 600x).
From: Janus, I. et al. Myocarditis in dogs: etiology, clinical and histopathological features. 11 cases (2007-2013).
Irish Vet J. 2010 67: 28.
This image is from an open access article distributed under the terms of the Creative Commons Attribution License.
Rabbit anti Borrelia burgdorferi:FITC
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- Borrelia burgdorferi
Antibody Quality and Performance Guarantee
| Rabbit anti Borrelia burgdorferi recognizes one of the causative agents of Lyme disease. B. burgdorferi is a spirochaete bacterium and one of the few pathogenic bacteria capable of surviving in the absence of iron. This antibody cross reacts with Treponema pallidum, Borrelia hermsii and Borrelia parkeri. |
- Target Species
- Bacterial
- Product Form
- Purified Ig conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
1% Bovine Serum Albumin - Immunogen
- Whole cell preparation from B. burgdorferi.
- Approx. Protein Concentrations
- IgG concentration 5 mg/ml
- Max Ex/Em
-
Fluorophore Excitation Max (nm) Emission Max (nm) FITC 490 525 - Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunofluorescence 1 |  |
1/10 | 1/50 |
- 1Acetone fixation is recommended for best results.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
References for Borrelia burgdorferi antibody
-
De Socio, G.V. et al. (2011) Malignant syphilis with ocular involvement in an HIV-infected patient.
Int J STD AIDS. 22: 298-300. -
Drago, F. et al. (2015) Primary syphilis of the oropharynx: an unusual location of a chancre.
Int J STD AIDS. 26 (9): 679-81. -
Drago, F. et al. (2012) Luetic lymphadenopathy despite negative serology
Int J STD AIDS. 23: 601-2. -
Haedersdal, M. & Weismann, K. (2000) Syphilitic chancre despite use of condoms: "condom chancre".
Acta Derm Venereol. 80 (3): 235-6. -
Janus, I. et al. (2014) Myocarditis in dogs: etiology, clinical and histopathological features (11 cases: 2007-2013).
Ir Vet J. 67 (1): 28. -
Briciu, V.T. et al. (2016) Immunohistochemistry and real-time PCR as diagnostic tools for detection of Borrelia burgdorferi sensu lato in ticks collected from humans.
Exp Appl Acarol. 69 (1): 49-60.
- RRID
- AB_616819
1439-9446
150586
157995
163976
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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