Cryptosporidium antibody | BEL 0126
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Mouse anti Cryptosporidium
- Product Type
- Monoclonal Antibody
- BEL 0126
| Mouse anti Cryptosporidium antibody, clone BEL 0126 recognizes a membrane antigen expressed by the oocysts of Cryptosporidium sp., an obligate enteric coccidian parasite of the phylum Apicomplexa that infects the gastrointestinal tract. The parasite is one of the most important enteric pathogens in both humans and animals (Rose et al. 2002). Since its first diagnosis in 1975 (Meisel et al. 1976), Cryptosporidiosis, has become one of the most prominent public health concerns worldwide (Rose et al. 2002).
Cryptosporidium oocysts are resistant to chlorine and their small size makes removal by filtration difficult. Alternative methods have been developed such as UV and ozone treatment alongside monitoring using Immunofluorescence screening (Rose et al. 2002).
Cryptosporidiosis is a disease affecting the intestines of mammals which is spread through the fecal-oral route. The main symptom of is self-limiting diarrhea in people with intact immune systems. However, in immunocompromised individuals, such as AIDS patients, infection can cause permanent & life-threatening diarrhea (Ma et al. 1984).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.09% Sodium Azide (NaN3)
- Carrier Free
- Purified cryptosporidium oocysts from bovine faeces.
- Approx. Protein Concentrations
- 1.0 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
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References for Cryptosporidium antibody
Mansfield, K.G. et al. (1997) Identification of an Enterocytozoon bieneusi-like microsporidian parasite in simian-immunodeficiency-virus-inoculated macaques with hepatobiliary disease.
Am J Pathol. 150: 1395-405.
Weigum, S.E. et al. (2016) Hollow silica microspheres for buoyancy-assisted separation of infectious pathogens from stool.
J Chromatogr A. 1466: 29-36.
Luka, G. et al. (2019) Label-Free Capacitive Biosensor for Detection of Cryptosporidium.
Sensors (Basel). 19 (2)Jan 10 [Epub ahead of print].
Sonzogni-desautels, K. et al. (2019) A protocol to count Cryptosporidium oocysts by flow cytometry without antibody staining.
PLoS Negl Trop Dis. 13 (3): e0007259.
Luka, G.S. et al. (2022) On-chip-based electrochemical biosensor for the sensitive and label-free detection of Cryptosporidium..
Sci Rep. 12 (1): 6957.
Meisel, J.L. et al. (1976) Overwhelming watery diarrhea associated with a cryptosporidium in an immunosuppressed patient.
Gastroenterology. 70: 1156-60.
Rose, J.B. et al. (2002) Risk and control of waterborne cryptosporidiosis.
FEMS Microbiol Rev. 26: 113-23.
Ma, P. (1984) Cryptosporidium and the enteropathy of immune deficiency.
J Pediatr Gastroenterol Nutr. 3 (4): 488-90.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Protozoan Products
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