IL-28A antibody | G02-3A6

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Mouse anti Human INTERLEUKIN-28A:Biotin

Product Type
Monoclonal Antibody
Clone
G02-3A6
Isotype
IgG1
Product Code Applications Pack Size List Price Quantity
MCA6211B
Datasheet
E
SDS
0.1 mg loader

Mouse anti Human interleukin-28A antibody, clone G02-3A6, recognizes interleukin-28A (IL-28A), also known as interferon lambda-2 (IFNL2). IL-28A is a member of the IL-10 interferon cytokine family. Similar to interferons, IL-28A is induced by viral infection and has anti-viral activity (Kempuraj et al. 2004). IL-28A can be produced by virus infected cells in the skin, leading to upregulation of proteins that inhibit virus replication. In this way, IL-28A may be involved with clearance of viruses in the skin (Wolk et al. 2010). Studies have also indicated that IL-28A is able to induce the innate and adaptive immune responses to engage in anti-tumor activity (Numasaki et al. 2007).

The biotinylated Mouse anti Human interleukin-28A antibody, clone G02-3A6 (MCA6211B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human interleukin-28A antibody, clone G04-5A2 (MCA6210GA) as the capture antibody.

Product Details

Target Species
Human
Product Form
Purified IgG conjugated to Biotin - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Immunogen
E. coli derived recombinant human full length interleukin-28a (Val26-Val200)
Approx. Protein Concentrations
IgG concentration 0.1 mg/ml
Fusion Partners
Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0

Storage Information

Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Guarantee
12 months from date of despatch

More Information

UniProt
Q8IZJ0
Entrez Gene
IL28A
GO Terms
GO:0009615 response to virus
GO:0005125 cytokine activity
GO:0005615 extracellular space
Regulatory
For research purposes only

Applications of IL-28A antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1.0 ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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