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CD127 antibody | AbD11590kb

Human anti Human CD127

Product Type
Monoclonal Antibody
Clone
AbD11590kb
Isotype
HuCAL/mouse IgG2a Fc
Specificity
CD127

Product Code Applications Pack Size List Price Your Price Qty
HCA402
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E F 0.1 mg loader
List Price Your Price
loader

Human anti Human CD127 antibody, clone AbD11590kb recognizes the alpha chain of the human interleukin-7 receptor (IL-7R), which is also known as CD127. CD127 is a ~65-75 kDa transmembrane glycoprotein that associates with the interleukin-2 receptor gamma chain to form the functional high affinity IL-7 receptor. CD127 is expressed on lymphoid precursors in the bone marrow, pro-B cells, a subpopulation of thymocytes, T-cells and inflammatory monocytes. CD127 is the specific receptor for IL-7 and the IL-7 receptor plays a critical role in lymphoid development.

Target Species
Human
Product Form
Recombinant chimeric human/mouse IgG2a antibody selected from the HuCAL phage display library and expressed in a human cell line. The antibody has variable regions of human origin and an Fc portion (including CH1 and CL domains) from mouse IgG2a. This antibody is supplied as a liquid.
Preparation
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Source
HKB-11
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Recombinant human IL-7 R alpha/CD127/Fc chimera
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
This product and/or its use is covered by claims of U.S. patents, and/or pending U.S. and non-U.S. patent applications owned by or under license to Bio-Rad Laboratories, Inc. See bio-rad.com/en-us/trademarks for details.

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Flow Cytometry
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Technical Advice
Recommended protocols and further information about HuCAL recombinant antibody technology can be found in the HuCAL Antibodies Technical Manual.

RRID
AB_2943335
UniProt
P16871
Entrez Gene
IL7R

HCA402

165785

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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