CCL13 antibody | B16-3D8
Mouse anti Human CCL13:Biotin
- Product Type
- Monoclonal Antibody
- Clone
- B16-3D8
- Isotype
- IgG1
- Specificity
- CCL13
Antibody Quality and Performance Guarantee
| Mouse anti Human CCL13 antibody, clone B16-3D8, recognizes CCL13, a member of the CC family of cytokines. CCL13, also known as MCP-4, is a 98 amino acid (aa) precursor protein which contains a 23 aa hydrophobic signal peptide that is cleaved to the mature form of the protein which is 75aa protein (8kDa). CCL13 is a chemoattractant for various cells including monocytes, T cells, immature dendritic cells and eosinophils (Entiquez & Garcia-Zepeda 2013). It has also been associated with various inflammatory diseases including asthma, arthritis, atherosclerosis and multiple sclerosis (Procaccini et al. 2015). CCL13 can bind to several chemokine receptors (CCR1, CCR2 and CCR3) to elicit chemoattractant responses. It is also known to induce degranulation of eosinophils and the secretion of pro-inflammatory cytokines. This biotinylated Mouse anti Human CCL13 antibody, clone B16-3D8 (MCA6177B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL13 antibody, clone B06-1G9 (MCA6176GA) as the capture antibody. |
- Target Species
- Human
- Product Form
- Purified IgG conjugated to Biotin - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin - Immunogen
- E. coli derived recombinant human full length CCL13 (Phe17-Thr98)
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human CCL13 | MCA6176GA | E | 0.1 mg |
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| Description | Mouse anti Human CCL13 | ||||||
- Synonyms
- MCP-4
- UniProt
- Q99616
- Entrez Gene
- CCL13
- GO Terms
- GO:0004871 signal transducer activity
- GO:0005615 extracellular space
- GO:0006874 cellular calcium ion homeostasis
- GO:0006935 chemotaxis
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0007267 cell-cell signaling
- GO:0008009 chemokine activity
MCA6177B
100005275
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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