Mumps Virus
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Native mumps virus preparation Native mumps virus contains a high concentration of virus and viral components. The preparation also contains some cellular material suspended in tissue culture medium (1969B).
Mumps virus is a member of the Paramyxoviridae family and is the causative agent of mumps. Mumps is most typically characterised by painful swelling of the salivary glands and fever. In some adult men, the virus might also infect the testicles, rarely causing sterility. The virus is spread by airborne droplets from the nose or throat and can have an incubation period of up to three weeks. Infected individuals are contagious from approximately 6 days before until about 9 days after the onset of symptoms. The disease is self-limiting and treatment involves controlling specific symptoms. An effective vaccine exists and may be given separately or as part of the MMR vaccine.
Mumps virus is a member of the Paramyxoviridae family and is the causative agent of mumps. Mumps is most typically characterised by painful swelling of the salivary glands and fever. In some adult men, the virus might also infect the testicles, rarely causing sterility. The virus is spread by airborne droplets from the nose or throat and can have an incubation period of up to three weeks. Infected individuals are contagious from approximately 6 days before until about 9 days after the onset of symptoms. The disease is self-limiting and treatment involves controlling specific symptoms. An effective vaccine exists and may be given separately or as part of the MMR vaccine.
Product Details
- Target Species
- Viral
- Product Form
- Inactivated Mumps virus - liquid
- Preparation
- Optimally infected cells are harvested, disrupted by sonication in culture medium and subjected to low speed centrifugation. The supernatant from the infected culture is concentrated by crossflow ultrafiltration.
The antigen preparation is inactivated using gamma radiation, which primarily damages viral genetic material. - Source
- Mumps virus, Enders strain, cultured in BSC-1 cells.
- Buffer Solution
- Culture medium 1969B
- Preservative Stabilisers
- None present
- Activity
- This product has been rendered inactive by standard procedures. However this material should still be handled as infectious and should be disposed of appropriately.
- Approx. Protein Concentrations
- Total protein concentration 2.35 mg/ml.
Storage Information
- Storage
- Store at -70oC.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. - Shelf Life
- 18 months from date of despatch.
More Information
- UniProt
- P21277 Related reagents
- GO Terms
- GO:0003723 RNA binding
- GO:0030529 ribonucleoprotein complex
- GO:0005198 structural molecule activity
- GO:0019013 viral nucleocapsid
- GO:0030430 host cell cytoplasm
- Regulatory
- For research purposes only
Applications of Mumps Virus
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Instructions For Use
- PIP014 should be sonicated immediately before use to ensure the preparation is uniform. The product may be used in a variety of immunoassay formats or may be further purified to meet the requirements of a particular assay format.
Copyright © 2018 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for Mumps Virus
-
Bhoj, V.G. et al. (2016) Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy.
Blood. 128 (3): 360-70.
