Chlamydia trachomatis is a common sexually transmitted bacterium. Chlamydia infection may cause proctitis, urethritis, trachoma (an eye infection and the leading cause of blindness worldwide) and infertility in both sexes. Prostatitis and epididymitis may occur in men and in women infection might lead to acute or chronic pelvic pain, pelvic inflammatory disease, cervicitis and ectopic pregnancy. In neonates the pathogen may cause trachoma and pulmonary complications.
Chlamydia trachomatis (PIP004 contains a high concentration of elementary bodies and chlamydial components in phosphate buffered saline. Residual host cellular material is present.
- Target Species
- Product Form
- Inactivated Chlamydia trachomatis - liquid
- Mouse L cells are infected with Chlamydia trachomatis LGV type II strain 434 elementary bodies. Optimally infected cells are harvested and disrupted by sonication in phosphate bufffered saline. Cellular debris is removed by centrifugation. The antigen preparation is inactivated using gamma radiation, which primarily damages chlamydial genetic material.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- This product has been rendered inactive by standard procedures. However this material should still be handled as infectious and should be disposed of appropriately.
- Approx. Protein Concentrations
- Total protein concentration 4.8 mg/ml
- Store at -70oC.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
- 18 months from date of despatch
- For research purposes only
Applications of Chlamydia trachomatis
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- Instructions For Use
- PIP004 should be sonicated immediately before use to ensure the preparation is uniform. The product may be used in a variety of immunoassay formats or may be further purified to meet the requirements of a particular assay format.