Blog Topic: Cancer

28 blog(s) on Cancer available

Neuroscience Cancer
How Lung Tumors Hijack Nerves to Dodge the Immune System

How Lung Tumors Hijack Nerves to Dodge the Immune System

In this blog, we discuss a recent paper by Wei et al. (2026), which uncovered a new mechanism by which tumor cells use the nervous system to bolster their position in the body.

Research Cancer
Let Sleeping Cells Lie: How Immune Cells Influence Metastatic Dormancy

Let Sleeping Cells Lie: How Immune Cells Influence Metastatic Dormancy

In this blog, we discuss how flow cytometry was used to examine metastatic dormancy, revealing a new role for immune cells in regulating this process.

Research Cancer
ADP-Ribosylation — A PARful Regulator of the Cell

ADP-Ribosylation — A PARful Regulator of the Cell

In this blog, we explore the intricate role of ADP-ribosylation in health and disease.

Research Cancer
Cell Cannibalism: An Appetite for Cancer?

Cell Cannibalism: An Appetite for Cancer?

For this Halloween blog, we’re taking a taste of something slightly different: cell cannibalism.

Guest Blog Cancer
CAR T-Cell Therapy — Driving the Future of Cancer Treatment

CAR T-Cell Therapy — Driving the Future of Cancer Treatment

In this blog, we discuss a recent study that used CAR T-cell therapy in a subset of gastric cancer patients

Research Cancer
The Role of Regulatory T Cells in the Fight against Lung Cancer

The Role of Regulatory T Cells in the Fight against Lung Cancer

In this blog, we discuss a recent paper studying the effect of depleting Tregs in lung cancer treatment.

Research Cancer
Bispecific Antibodies: A New-Age Cancer Immunotherapy to Battle Solid Tumors

Bispecific Antibodies: A New-Age Cancer Immunotherapy to Battle Solid Tumors

In this blog, we discuss how bsAbs are gaining traction as a novel treatment strategy for NSCLC and showing great promise in combination therapy in clinical trials.

Research Cancer
Could Salmonella Be Our Unlikely Ally in the Fight against Cancer?

Could Salmonella Be Our Unlikely Ally in the Fight against Cancer?

In this blog, we discuss recent advances in bacterial cancer therapy (BCT).

Research Cancer
Tumor Patrol: Dendritic Cells in Anti-Tumor Immunity

Tumor Patrol: Dendritic Cells in Anti-Tumor Immunity

In this blog, we discuss new insights about how DCs control immune responses in the tumor microenvironment and the implications for immunotherapy.

Research Cancer
Tipping the Balance: Could ILCs Be Used for Cancer Immunotherapy?

Tipping the Balance: Could ILCs Be Used for Cancer Immunotherapy?

In this blog, we discuss the role of innate lymphoid cells (ILCs) in cancer and their potential as therapeutic targets.

Research Cancer
Tiny Gut Microbes Boost the Immune System to Fight against Cancer

Tiny Gut Microbes Boost the Immune System to Fight against Cancer

In this blog, we will delve into how the microorganisms residing in our intestines can impact the anti-tumor response triggered by immune checkpoint blockade therapy.

Research Cancer
Good TIMEs: Using the Tumor Microenvironment to Predict Response to Treatment

Good TIMEs: Using the Tumor Microenvironment to Predict Response to Treatment

In this blog, we discuss a recent study by Misetic et al. (2023) in which they investigated the mechanisms behind the immune-regulatory role of the TIME and how components of the TIME could be used as biomarkers to predict response to immunotherapy.

Research Cancer
Monoclonal Antibodies for the Treatment of Endometrial Cancer

Monoclonal Antibodies for the Treatment of Endometrial Cancer

In this blog, we discuss the recent approval of dostarlimab (Jemperli), a PD-1 inhibitor, in combination with chemotherapy as a first-line treatment for endometrial cancer.

Research Cancer
Can Exercise Boost Anticancer Immunity?

Can Exercise Boost Anticancer Immunity?

In this blog, we discuss some of the research investigating the beneficial effects of exercise on anticancer immunity.

Guest Blog Cancer
Spot the Difference: Why There Are Two Ways to Develop Melanoma

Spot the Difference: Why There Are Two Ways to Develop Melanoma

This blog discusses how both UV radiation and non-UV pathways can promote melanoma.

Research Cancer
It Takes a Village: How a Dysfunctional Cellular Community Could Raise a Melanoma

It Takes a Village: How a Dysfunctional Cellular Community Could Raise a Melanoma

2022 Bio-Rad Science Writing Competition winning article. Katie Lee uses an “it takes a village” analogy to explain how it is the combination of multiple factors that tips the balance toward melanoma formation.

Guest Blog Cancer
350+ Ways pRB is More than Just E2F Regulation

350+ Ways pRB is More than Just E2F Regulation

In this guest blog, Sabine Hahn, a researcher who focuses on the dynamic regulation of chromatin structure and how that influences chromosome segregation during mitosis, discusses pRB’s vital role in cancer epigenetics.

Guest Blog Cancer
The Cancer-Therapy Arms Race

The Cancer-Therapy Arms Race

In this guest blog, Grace Gregory discusses Non-small Cell Lung Cancer (NSCLC), some of the different treatment approaches being used, and why finding the most appropriate treatment for NSCLC isn’t always straightforward

Research Cancer
The Buzz Around STING Agonists

The Buzz Around STING Agonists

This blog gives an overview of the history of the STimulator of Interferon Genes (STING) pathway and highlights why pharmaceutical companies are making a beeline to develop STING agonists.

Research Cancer
A Balancing AKT: the E17K Hotspot Mutation and How It Defines Cancer

A Balancing AKT: the E17K Hotspot Mutation and How It Defines Cancer

AKT is an extremely important kinase in human health, playing an intricate role in coordinating fundamental signaling pathways. This blog discusses a “hotspot” mutation, called E17K, that can cause constant AKT activation and wreak havoc on cell homeostasis.

Research Cancer
Slash the Tires Instead to Slow Down Prostate Cancer

Slash the Tires Instead to Slow Down Prostate Cancer

This article was awarded 3rd place in the 2020 Bio-Rad Science Writing Competition.

Research Cancer
The Importance of Phosphorylation Events in Cancer

The Importance of Phosphorylation Events in Cancer

This blog discusses phosphorylation, a common regulator of signal transduction pathways and the role of inappropriate phosphorylation events in cancer.

Research Cancer
Can Medicine Trust Your Gut Organoids?

Can Medicine Trust Your Gut Organoids?

This blog focuses on gastrointestinal organoids and their role in advancing cancer research and therapy.

Research Cancer
Checkmate: Beating Cancer through the PD-1 Pathway

Checkmate: Beating Cancer through the PD-1 Pathway

This blog discusses the PD-1 (programmed cell death-1) pathway and two licensed immunotherapy drugs that target it, pembrolizumab and nivolumab.

Research Cancer
When ubiquitination goes bad, knock it out for effective cancer therapy

When ubiquitination goes bad, knock it out for effective cancer therapy

This blog post highlights the key ubiquitin E3 ligases currently considered molecular drug targets.

Research Cancer
Inducing macrophages that work against rather than for cancer

Inducing macrophages that work against rather than for cancer

Within the immune response to cancer macrophages present both a problem and solution. This post describes how they can assist with tumor clearance.

Research Cancer
GATA transcription factors and their role in cancer diagnosis and prognosis

GATA transcription factors and their role in cancer diagnosis and prognosis

The GATA family of transcription factors is emerging as key players in establishing new biomarkers for rapid and accurate detection of cancer. Find out more...

Research Cancer
Inheriting mutant tumor suppressor genes increases your risk for cancer

Inheriting mutant tumor suppressor genes increases your risk for cancer

This post describes how mutations in proto-oncogenes and tumor suppressor genes account for tumorigenesis.