Blog Topic: Immunology

36 blog(s) on Immunology available

Could Mindfulness De-Stress Your Immune System?

Could Mindfulness De-Stress Your Immune System?

In this blog, we discuss the effect of stress on the immune system and whether mindfulness has scientific merit in counteracting its influence.

Training the Immune Mind: Advancing Vaccine Design to Educate T Cells

Training the Immune Mind: Advancing Vaccine Design to Educate T Cells

In this blog, we will discuss the role of T cells in the vaccine-induced immune response and the key challenges in achieving long-lasting and broad-spectrum immunity.

Is the Future of CAR T-Cell Therapy Off-the-Shelf? Genetic Engineering Could Be the Answer

Is the Future of CAR T-Cell Therapy Off-the-Shelf? Genetic Engineering Could Be the Answer

In this blog, we discuss how CAR T cell-therapy could be used to treat autoimmune disease.

The Importance of Sleep for the Immune System

The Importance of Sleep for the Immune System

In this blog, we delve into the specific effects of sleep on the immune response.

No Smoke without Fire: The Blazing Effects of Smoking on the Immune System

No Smoke without Fire: The Blazing Effects of Smoking on the Immune System

In this blog, we discuss a new study highlighting the negative impact of smoking on the immune system.

Insights From Immunologists: Professor Hugh Perry

Insights From Immunologists: Professor Hugh Perry

In this blog, we speak to Professor Hugh Perry, who collaborated with Siamon to advance our understanding of macrophages in the brain, about his career journey in neuroimmunology.

Therapeutic Dilemmas: Exploring the Dual Nature of IL-17 in Immune Responses

Therapeutic Dilemmas: Exploring the Dual Nature of IL-17 in Immune Responses

In this blog, we will discuss the pathological implications associated with IL-17A and current therapeutic treatments for diseases.

Insights From Immunologists: Professor Hsi-Hsien Lin

Insights From Immunologists: Professor Hsi-Hsien Lin

In this blog, we speak to Professor Hsi-Hsien Lin, who worked as a postdoctoral researcher in Siamon’s lab, about his career to date.

Insights From Immunologists: Professor Alan Ezekowitz

Insights From Immunologists: Professor Alan Ezekowitz

We spoke to Professor Alan Ezekowitz, who undertook his doctoral studies in Siamon’s lab, about his diverse scientific career.

Insights From Immunologists: Professor Jon Austyn

Insights From Immunologists: Professor Jon Austyn

We spoke to Professor Jon Austyn, Siamon’s first graduate student who carried out the original research identifying F4/80, about his remarkable scientific career.

The Past, the Present, and the Future of Immunoglobulin M

The Past, the Present, and the Future of Immunoglobulin M

In this blog, we discuss a recent discovery showing that the protein CD5L is associated with immunoglobulin M in the circulation.

No Guts, No Glory: Innovative Treatments for Crohn’s Disease

No Guts, No Glory: Innovative Treatments for Crohn’s Disease

In this blog, we will discuss the different methods utilized to treat Crohn's disease, including the more commonly used biologics and the newly approved Janus kinase (JAK) inhibitor, upadacitinib.

Siamon Gordon: The Father of F4/80

Siamon Gordon: The Father of F4/80

In this blog Siamon Gordon tells us about his life and career, with an impressive scientific pedigree and immense contributions to macrophage research over the past 50 years

The TLR7/IRF-5 Axis in HIV: A Matter of Life and Cell Death?

The TLR7/IRF-5 Axis in HIV: A Matter of Life and Cell Death?

In this blog, we discuss a recent study by Carmona-Pérez et al., in which they investigate the role of the Toll-like receptor (TLR) 7/interferon regulatory factor 5 (IRF-5) axis in the predisposition of CD4 T cells to apoptosis during HIV infection.

From Powerhouses to Inferno: A Mitochondrial Messenger Fuels Inflammation

From Powerhouses to Inferno: A Mitochondrial Messenger Fuels Inflammation

In this blog, we discuss the concept of immunometabolism, including a new study published by Hooftman et al. (2023) in Nature showing how a molecule derived from mitochondrial metabolism can trigger inflammation, providing insights into the versatile functions of these organelles beyond energy production.

Immune Cells Get an Upgrade: A Stronger Defense against Cancer

Immune Cells Get an Upgrade: A Stronger Defense against Cancer

This blog takes a look at recent advances in CAR T-cell therapies, which allow CAR expression and release of cytokines in a controllable manner.

Unlocking the Secrets of Neuroimmunology: Connecting What Belongs Together

Unlocking the Secrets of Neuroimmunology: Connecting What Belongs Together

In this blog, Patrick Penndorf writes about neuroimmunology, the connection between neuroscience and immunology research. This blog was awarded joint 2nd place in the 2022 Bio-Rad Science Writing Competition.

A PITiful End for a Pathogen

A PITiful End for a Pathogen

In this guest blog, Temitayo Bamgbose, a graduate student at Louisiana State University Health Sciences Center, Shreveport, discusses PITs, a tactic utilized by the immune system to eliminate pathogens.

Gamma Delta T cells: The Unsung Heroes of Immunology

Gamma Delta T cells: The Unsung Heroes of Immunology

This blog was awarded 3rd place in the 2021 Bio-Rad Science Writing Competition.

How Do Pattern Recognition Receptors Help Mount an Immune Response?

How Do Pattern Recognition Receptors Help Mount an Immune Response?

This guest blog takes a look at pattern recognition receptors and how they mount an immune response against viruses.

Looking Beneath the Surface: Viral Clearance by Anti-Nucleoproteins

Looking Beneath the Surface: Viral Clearance by Anti-Nucleoproteins

This guest blog examines a paper published by Caddy et al. (2020) in EMBO Journal that sheds new light on anti-nucleoprotein antibodies and clearance of viral infections that could have important implications for vaccine design.

A T Cell for Your Thoughts?

A T Cell for Your Thoughts?

Can T cells influence our brain function? In this guest blog, we explore the contribution of T cells to learning and memory.

A MASTer Immune cell

A MASTer Immune cell

In this guest blog, we take a look at some of the areas outside of allergy that mast cells play a role in.

Navigating the Deadly Cytokine Storm

Navigating the Deadly Cytokine Storm

Sometimes our immune systems launch an excessive, disproportionate response to a real infection, called a "cytokine storm". This blog looks at cytokine storms and the role they may play in COVID-19 pathogenesis.

Tumors Sweet Success due to Macrophage Polarization

Tumors Sweet Success due to Macrophage Polarization

This blog discusses a recent study by Bohn et al. (2018) that highlights a mechanism that melanoma utilizes to subvert the immune response.

Manifestation of Ghosts Exacerbates Asthma

Manifestation of Ghosts Exacerbates Asthma

Krishnamoorthy et al. (2018) have identified enucleated neutrophil cell bodies, known as ‘ghosts’, as driving Th17 cell inflammation in severe asthma.

The Good, the Bad and the Ugly Side of the Gut Microbiome

The Good, the Bad and the Ugly Side of the Gut Microbiome

This blog takes a look at how gut microbiota may play a role in anti-tumor immune responses.

Th2A Cells — the Latest T Helper Cell Subset and its Role in Allergy

Th2A Cells — the Latest T Helper Cell Subset and its Role in Allergy

Th2A cells are a recently identified subset of T helper cells type 2 (Th2). This blog looks at the role of Th2A cells in allergy.

Inking the Immune System: How Macrophages Make Tattoos Last

Inking the Immune System: How Macrophages Make Tattoos Last

Baranska et al. (2018) identify macrophage dynamics as being key to tattoos lasting. This blog examines why tattoos are so difficult to remove.

How Good Bacteria Protect Us from Pathogenic Infection

How Good Bacteria Protect Us from Pathogenic Infection

This blog describes studies demonstrating the beneficial role of commensal bacteria in treating microbial infections and antibiotic resistance.

How to Identify Major Immune Cell Types by Their CD Marker Expression

How to Identify Major Immune Cell Types by Their CD Marker Expression

Learn how a new tool from Bio-Rad simplifies knowing what markers to use to identify certain immune cell types.

Macrophages, obesity and insulin resistance

Macrophages, obesity and insulin resistance

This blog post describes the mechanisms by which macrophages induce insulin resistance in the obese state.

What do monocytes have to do with the heart?

What do monocytes have to do with the heart?

This post describes the role of monocytes in heart disease and whether monocyte infiltration into the heart exacerbates disease or aids in its repair.

Monocyte-based cell therapy for treating diseases

Monocyte-based cell therapy for treating diseases

This blog post discusses recent pre-clinical studies that suggest monocytes could be applied in a related manner to the treatment of diseases.

Immunological memory is no longer a unique trait of adaptive immune cells

Immunological memory is no longer a unique trait of adaptive immune cells

The new finding of trained immunity challenges the basic tenets of immunology, blurring the line that separates innate and adaptive immunity.

Four virus serotypes…One Dengue vaccine?

Four virus serotypes…One Dengue vaccine?

Have a group of researchers really found the key to a cure to the currently incurable Dengue virus? Find out here...