Yellow Fever Virus antibody | 2D12 (0G5)
Mouse anti Yellow Fever Virus
- Product Type
- Monoclonal Antibody
- Clone
- 2D12 (0G5)
- Isotype
- IgG2a
- Specificity
- Yellow Fever Virus
Mouse anti Yellow fever virus antibody, clone 2D12 recognizes the envelope protein of the wild (Asibi) and vaccine strains of yellow fever virus. Mouse anti Yellow fever virus antibody, clone 2D12 has been reported to have neutralizing activity against the Asibi strain (Schlessinger et al. 1984). No cross reactivity with other flaviviruses has been reported. |
- Target Species
- Viral
- Product Form
- Ascites - Liquid
- Preservative Stabilisers
- None Present
- Immunogen
- 17D strain of yellow fever virus
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Functional Assays | |||
Immunofluorescence |
References for Yellow Fever Virus antibody
-
Schlesinger, J.J. et al. (1983) Monoclonal antibodies distinguish between wild and vaccine strains of yellow fever virus by neutralization, hemagglutination inhibition, and immune precipitation of the virus envelope protein.
Virology. 125 (1): 8-17. -
Schlesinger, J.J. & Brandriss, M.W. (1983) 17D yellow fever virus infection of P388D1 cells mediated by monoclonal antibodies: properties of the macrophage Fc receptor.
J Gen Virol. 64 (Pt 6): 1255-62. -
Schlesinger, J.J. et al. (1984) Analysis of 17D yellow fever virus envelope protein epitopes using monoclonal antibodies.
J Gen Virol. 65 ( Pt 10): 1637-44. -
Gandini, M. et al. (2011) Dengue-2 and yellow fever 17DD viruses infect human dendritic cells, resulting in an induction of activation markers, cytokines and chemokines and secretion of different TNF-α and IFN-α profiles.
Mem Inst Oswaldo Cruz. 106 (5): 594-605. -
Monath, T.P. et al. (1986) Sensitive and specific monoclonal immunoassay for detecting yellow fever virus in laboratory and clinical specimens.
J Clin Microbiol. 23 (1): 129-34. -
Brandriss, M.W. et al. (1986) Lethal 17D yellow fever encephalitis in mice. I. Passive protection by monoclonal antibodies to the envelope proteins of 17D yellow fever and dengue 2 viruses.
J Gen Virol. 67 ( Pt 2): 229-34. -
Op De Beeck, A. et al. (2003) Role of the transmembrane domains of prM and E proteins in the formation of yellow fever virus envelope.
J Virol. 77 (2): 813-20. -
Izurieta, R.O. et al. (2009) Anamnestic immune response to dengue and decreased severity of yellow Fever.
J Glob Infect Dis. 1 (2): 111-6.
View The Latest Product References
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Thonnon, J. et al. (1998) Re-emergence of yellow fever in Senegal in 1995.
Am J Trop Med Hyg. 59 (1): 108-14. -
Thonnon, J.et al. (1998) Yellow fever outbreak in Kaffrine, Senegal 1996: epidemiological and entomological findings.
Trop Med Int Health. 3 (11): 872-7. -
Op De Beeck, A. et al. (2004) The transmembrane domains of the prM and E proteins of yellow fever virus are endoplasmic reticulum localization signals.
J Virol. 78 (22): 12591-602. -
Ciczora, Y. et al. (2010) Identification of a dominant endoplasmic reticulum-retention signal in yellow fever virus pre-membrane protein.
J Gen Virol. 91 (Pt 2): 404-14. -
Vratskikh, O. et al. (2013) Dissection of antibody specificities induced by yellow fever vaccination.
PLoS Pathog. 9 (6): e1003458.
- RRID
- AB_619294
9801-8006
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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