Papillomavirus 11 Protein E7 Antibody | 711-66

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  • Mouse anti Human Papillomavirus 11 Protein E7
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Monoclonal Antibody
  • Clone
    711-66
  • Isotype
    IgG1
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA2852E, WBdatasheet pdfdatasheet pdf0.2 mg
    MCA2852
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Mouse anti Human Papillomavirus 11 Protein E7 antibody, clone 711-66 recognizes the E7 protein of human papilloma virus 11. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Type 11 HPV is a low risk type that causes anogenital warts and is not linked with cervical cancer. In rare cases HPV-11 may cause respiratory papillomatosis, where warts form on the larynx or other areas of the respiratory tract. The viral protein E7 binds to Rb (retinoblastoma protein) and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. This binding is of much lower affinity than the high-risk HPV E7 proteins. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection.

      Mouse anti Human Papillomavirus 11 Protein E7 antibody, clone 711-66 cross-reacts minimally with the E7 protein of HPV-16 and HPV-18.
    • Intended Use
    • Target Species
      Viral
    • Product Form
      Purified IgG - liquid
    • Reconstitution
    • Preparation
      Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    • Preservative Stabilisers
      0.09% Sodium azide
    • Immunogen
      Protein E7 from human papillomavirus 11.
    • Purity
    • Approx. Protein Concentrations
      IgG concentration 1.0mg/ml
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      Phosphate buffered saline
    • Fusion Partners
      Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
    • Storage
      Store at +4oC or at -20oC if preferred.
      Storage in frost-free freezers is not recommended.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody.
    • Shelf Life
      18 months from date of despatch.
    • GO Terms
      regulation of transcription, DNA-dependent
      DNA binding
      evasion by virus of host immune response
      intracellular
      metal ion binding
      sequence-specific DNA binding transcription factor activity
    • UniProt
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISA
      Western Blotting

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Papillomavirus 11 Protein E7 Antibody Formats

    Formats Clone Applications Sizes available
    Papillomavirus 11 Protein E7 Antibody : Purified 711-66 E, WB 0.2 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

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