Marek's Disease Virus Antibody | 14C8

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  • Mouse anti Marek's Disease Virus
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  • Product Type
    Monoclonal Antibody
  • Clone
    14C8
  • Isotype
    IgG1
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    MCA2662Edatasheet pdfdatasheet pdf0.2 mg
    MCA2662
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
    -
    • Mouse anti Marek's Disease Virus antibody, clone 14C8 detects Marek's Disease Virus (MDV), an oncogenic avian virus that is economically important in the chicken industry. MDV is a double stranded DNA herpesvirus, which is highly contagious, and results in aggressive T-cell lymphomas.

      Infection of MDV occurs via the respiratory tract, where its uptake by macrophages and dendritic cells allows it to be transported in the bloodstream to visceral organs and peripheral nerves. Here MDV results in neoplasms of the heart, liver, kidney and gonads, and polyneuritis. It can also lead to asymmetric paralysis of one or more limbs, difficulty of breathing, dilation of the crop and death in up to 80 percent of birds.

      Marek's disease is the only virus-induced tumour disease for which vaccination is available.
    • Intended Use
    • Target Species
      Viral
    • Product Form
      Purified IgG - liquid
    • Reconstitution
    • Preparation
      Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    • Preservative Stabilisers
      0.09%Sodium Azide (NaN3)
    • Immunogen
      Marek's disease virus.
    • Purity
    • Approx. Protein Concentrations
      IgG concentration 1.0mg/ml
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      Phosphate buffered saline
    • Storage
      Store at +4oC or at -20oC if preferred.
      Storage in frost-free freezers is not recommended.
      This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISA

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Marek's Disease Virus Antibody Formats

    Formats Clone Applications Sizes available
    Marek's Disease Virus Antibody : Purified 14C8 E 0.2 mg
    • Copyright © 2016 Bio-Rad

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

              Further Reading

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