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Nmdar/NR1/N1 Antibody

Nmdar/NR1/N1 Antibody gallery image 1

Western blot of HEK 293 cells expressing: (1) NR1 subunit containing the N1 and C2' insert: (2 and 3) NR1 subunit containing the C1/C2' insert: (4) without NR1 expression

  • Nmdar/NR1/N1 Antibody thumbnail image 1
  • Rabbit anti NMDA Receptor/NR1 Subunit/Splice Variant N1
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  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP991C, WBdatasheet pdfdatasheet pdf25 µg
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    • Rabbit anti Rat NMDA Receptor/NR1 Subunit/Splice Variant N1 antibody recognizes the 120 kDa NR1 subunit of the NMDA (N-methyl-D-aspartate) receptor, containing the N1 splice variant insert. Rabbit anti Rat NMDA Receptor/NR1 Subunit/Splice Variant N1 antibody does not recognize the NR1 subunit, where the N1 splice variant insert is absent.

      Receptors for NMDA (NMDAR) belong to a group of ionotropic glutamate receptors which play a key role in the mediation of glutamate neurotransmission within the mammalian central nervous system (CNS), including involvement in memory and learning processes. Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage-dependent Mg2+ blockade and high Ca2+ permeability.

      The NR1 subunit has eight splice variants, arising from either the deletion or insertion of three exon cassettes within the C-terminal (C1, C2) and N-terminal (N1) NR1 domains. These splice variants differ in both their expression and pharmacological properties.
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Immunohistology - Frozen1/10001/2000
      Western Blotting1/1000

    • Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
    • Instructions For Use

    Additional Nmdar/NR1/N1 Antibody Formats

    Formats Applications Sizes available
    Nmdar/NR1/N1 Antibody : Purified C, WB 25 µg
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

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      Goat anti Rabbit IgG (Fc):FITCSTAR121F1 mgF
      Sheep anti Rabbit IgG:FITCSTAR34B1 mgC, F
      Goat anti Rabbit IgG (Fc):HRPSTAR121P1 mgE, WB
      Goat anti Rabbit IgG (H/L):HRPSTAR124P1 mgC, E, WB
      Sheep anti Rabbit IgG:HRP (Multi Adsorbed)STAR541 mgC, E, WB
      Sheep anti Rabbit IgG:RPESTAR35A1 mlF

      Recommended Negative Isotype Control

        Useful Reagents

          DescriptionProduct CodePack SizeApplicationsList PriceQuantity
          TidyBlot Western Blot Detection Reagent:HRPSTAR209P0.5 mlWB*

          Recommended Positive Controls

            Histology Controls

                • Product Images

                • Nmdar/NR1/N1 Antibody thumbnail image 1

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