GABA B Receptor 1 (pSer923) Antibody

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GABA B Receptor 1 (pSer923) Antibody gallery image 1

Western blot of a rat synaptic membrane showing phosphospecific immunolabeling of the ~102 kDa GABAB R2 protein phosphorylated at Ser923

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  • GABA B Receptor 1 (pSer923) Antibody thumbnail image 1
  • Rabbit anti GABA B Receptor 1 (pSer923)
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  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP1300WB*datasheet pdfdatasheet pdf0.1 ml
    AHP1300
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Rabbit anti Rat GABA B receptor 1 (pSer923) antibody recognizes gamma-aminobutyric acid type B receptor subunit 1 (GABA B receptor 1) when phosphorylated at serine 923.

      GABA B receptors are heterodimeric G-protein coupled receptors which are important mediators of slow neuronal inhibition in the mammalian central nervous system. The functional expression of GABA B receptors on plasma membranes is dependent upon the co-expression of GABR1 and GABR2 (gamma-aminobutyric acid B (GABA B) receptor 2). Phosphorylation of GABR1 at the serine 923 site may be an important factor in the regulation of GABA B receptor function.

      Abnormalities in the expression or function of GABAB receptors are associated with temporal lobe epilepsy (Gambardella et al. 2003).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting(1)1/1000
      (1)
      For the detection of phosphoproteins, tyrosine phosphatase inhibitors such as 1mM Sodium Orthovanadate should be added to the sample buffer. Milk or other casein-based blocking solutions are not recommended as casein is a phosphoprotein and its use can result in high background.

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
      AHP1300 detects a band of approximately 102kDa in rat synaptic membrane cell lysates.
    • Instructions For Use

    Additional GABA B Receptor 1 (pSer923) Antibody Formats

    Formats Applications Sizes available
    GABA B Receptor 1 (pSer923) Antibody : Purified WB* 0.1 ml
    • Copyright © 2017 Bio-Rad Antibodies (formerly AbD Serotec)

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      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

              References

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