OBT0969 recognises the RH strain of the coccidian parasite Toxoplasma gondii, a causitive agent of toxoplasmosis in many species of warm blooded animals. Felids are the only definitive host for T. gondii.. Infection is usually sub-clinical with symptoms depending on the level of tachyzoite release, the ability of the host to limit tachyzoite spread and the organs damaged by the tachyzoites. Immunocompetent adult animals generally limit tachyzoite spread and infection remains subclinical. However in young or immunocompromised animals infection can develop to an acute gereralised toxoplasmosis. T. gondii is an important zoonotic agent with up to 60% of some human populations demonstrating Serum IgG titers to the organism. These are likely to be persistently infected. The organism is of particular concern in immunocomprimised individuals such as those with HIV infection, who become increasingly susceptible to the organism as the immune system wanes. Infection is also of considerable concern in pregnant women as it can migrate across the placenta and cause birth defects in human foetuses.
Ig fraction - liquid
0.1% Sodium Azide (NaN3)
Tachyzoites of RH strain of Toxoplasma gondii.
Approx. Protein Concentrations
Ig concentration 4 mg/ml
Reagents In The Kit
Preparing The Antibody
Phosphate buffered saline
Store at +4oC or at -20oC if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
18 months from date of despatch.
For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.