Thyroxine Binding Globulin
Purified Human thyroxine binding globulin is native human thyroxine binding globulin (TBG) purifired from serum. TBG is a serpin produced in the liver with high affinity for the thyroid hormones T3 and T4. TBG reversibly binds T3 and T4, enabling their circulation around the bloodstream.
- Product Form
- Purified protein from human serum - lyophilised
- Reconstitute with sterile PBS containing 0.15M NaCl. For long term storage the addition of 0.09% sodium azide is recommended.
N.B. For functional studies do not add sodium azide.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Human serum
- Buffer Solution
- Ammonium bicarbonate
- Preservative Stabilisers
- None present.
- >98% by SDS PAGE
- Molecular Weight
- 55 kD
- Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- 12 months from date of reconstitution.
- P05543 Related reagents
- Entrez Gene
- SERPINA7 Related reagents
- GO Terms
- GO:0004867 serine-type endopeptidase inhibitor activity
- GO:0005615 extracellular space
- For research purposes only
Applications of Thyroxine Binding Globulin
|Application Name||Verified||Min Dilution||Max Dilution|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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