Thyroxine Binding Globulin

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Thyroxine Binding Globulin

Product Type
Purified Protein
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
8970-1004 E 1 mg
Purified Human thyroxine binding globulin is native human thyroxine binding globulin (TBG) purifired from serum. TBG is a serpin produced in the liver with high affinity for the thyroid hormones T3 and T4. TBG reversibly binds T3 and T4, enabling their circulation around the bloodstream.

Product Details

Product Form
Purified protein from human serum - lyophilised
Reconstitution
Reconstitute with sterile PBS containing 0.15M NaCl. For long term storage the addition of 0.09% sodium azide is recommended.
N.B. For functional studies do not add sodium azide.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
Source
Human serum
Buffer Solution
Ammonium bicarbonate
Preservative Stabilisers
None present.
Purity
>98% by SDS PAGE
Molecular Weight
55 kD

Storage Information

Storage
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of reconstitution.

More Information

UniProt
P05543 Related reagents
Entrez Gene
SERPINA7 Related reagents
GO Terms
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005615 extracellular space
Regulatory
For research purposes only

Applications of Thyroxine Binding Globulin

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.