Myelin Proteolipid Protein

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Synthetic Human Myelin Proteolipid Protein

Product Type
Purified Protein
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
6420-5150 E 50 µg
Purified Myelin Proteolipid Protein is a peptide with the sequence CGGQKGRGSRGQH, representing amino acids 119-130 of human myelin proteolipid protein. An additional cysteine has been conjugated to the N-terminus.

Myelin proteolipid protein, the major myelin protein from the central nervous system, plays an important role in the formation and maintenance of the multilamellar structure of myelin.

Product Details

Target Species
Human
Product Form
Synthetic peptide - lyophilised
Reconstitution
Reconstitute in sterile distilled water to give a concentrated stock solution => 2mg/ml.
Preparation
Solid phase synthesis
Buffer Solution
Acetate salt
Preservative Stabilisers
None present
Purity
HPLC: >80%

Storage Information

Storage
Prior to reconstitution store at +4oC.
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. This product should be stored undiluted.
Shelf Life
12 months from date of reconstitution.

More Information

UniProt
P60201 Related reagents
Entrez Gene
PLP1 Related reagents
GO Terms
GO:0016021 integral to membrane
GO:0007268 synaptic transmission
GO:0008219 cell death
Regulatory
For research purposes only

Applications of Myelin Proteolipid Protein

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Product Specific References

References for Myelin Proteolipid Protein

  1. Bahbouhi, B. et al. (2010) T cell recognition of self-antigen presenting cells by protein transfer assay reveals a high frequency of anti-myelin T cells in multiple sclerosis.
    Brain. 133 (Pt 6): 1622-36.
  2. Becker, K.J. et al. (2011) Autoimmune responses to the brain after stroke are associated with worse outcome.
    Stroke. 42: 2763-9.