Low Density Lipoprotein

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Native Human Low Density Lipoprotein

Product Type
Purified Protein
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
5685-3204 FN 5 mg
Low density lipoproteins transport cholesterol and triglycerides to cells requiring them. They are delivered via LDL receptors in the plasma membrane, via clathrin coated pits to the endosomal pathway for further processing.

Product Details

Target Species
Human
Product Form
Purified from human plasma - liquid
Preparation
Purified via ultracentrifugation to homogeneity as determined via agarose gel electrophoresis.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.3mM EDTA
Activity
This lot of material has been evaluated for receptor binding to human skin fibroblasts in conjunction with Dil-LDL.
Approx. Protein Concentrations
Total protein concentration 5.0 mg/ml

Storage Information

Storage
Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Precipitation may occur after prolonged storage. This is normal and can be removed by centrifugation. This product has been aseptically packaged and membrane filtered. Handle aseptically.
Shelf Life
Please see label for expiry date.

More Information

Regulatory
For research purposes only

Applications of Low Density Lipoprotein

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Functional Assays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Product Specific References

References for Low Density Lipoprotein

  1. Lufino, M.M. et al. (2016) The infectious BAC genomic DNA expression library: a high capacity vector system for functional genomics.
    Sci Rep. 6: 28644.
  2. Spitsin, S. et al. (2017) Antiinflammatory effects of aprepitant coadministration with cART regimen containing ritonavir in HIV-infected adults.
    JCI Insight. 2 (19) Oct 05 [Epub ahead of print].
  3. Xiong, W. et al. (2017) The macrophage C-type lectin receptor CLEC5A (MDL-1) expression is associated with early plaque progression and promotes macrophage survival.
    J Transl Med. 15 (1): 234.