Low Density Lipoprotein
Low density lipoproteins transport cholesterol and triglycerides to cells requiring them. They are delivered via LDL receptors in the plasma membrane, via clathrin coated pits to the endosomal pathway for further processing.
- Target Species
- Product Form
- Purified from human plasma - liquid
- Purified via ultracentrifugation to homogeneity as determined via agarose gel electrophoresis.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.3mM EDTA
- This lot of material has been evaluated for receptor binding to human skin fibroblasts in conjunction with Dil-LDL.
- Approx. Protein Concentrations
- Total protein concentration 5.0 mg/ml
- Store at +4oC. DO NOT FREEZE.
This product should be stored undiluted. Precipitation may occur after prolonged storage. This is normal and can be removed by centrifugation. This product has been aseptically packaged and membrane filtered. Handle aseptically.
- Shelf Life
- Please see label for expiry date.
- For research purposes only
Applications of Low Density Lipoprotein
|Application Name||Verified||Min Dilution||Max Dilution|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2018 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for Low Density Lipoprotein
Lufino, M.M. et al. (2016) The infectious BAC genomic DNA expression library: a high capacity vector system for functional genomics.
Sci Rep. 6: 28644.
Spitsin, S. et al. (2017) Antiinflammatory effects of aprepitant coadministration with cART regimen containing ritonavir in HIV-infected adults.
JCI Insight. 2 (19) Oct 05 [Epub ahead of print].
Xiong, W. et al. (2017) The macrophage C-type lectin receptor CLEC5A (MDL-1) expression is associated with early plaque progression and promotes macrophage survival.
J Transl Med. 15 (1): 234.