Inhibin Beta A

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Recombinant Human Inhibin Beta A

Product Type
Recombinant Protein
Product Code Applications Pack Size List Price Quantity
PHP194
Datasheet
E WB
SDS
10 µg loader

Recombinant Human inhibin beta A is a single monomeric non-glycosylated polypeptide chain containing 116 amino acid fragment corresponding to residues 311-426 of the inhibin beta A (INHBA) subunit.

INHBA is a member of the transforming growth factor-beta family which, in combination with the alpha subunit, forms an inhibitor of pituitary follicle-stimulating hormone (FSH) secretion, and when combined with itself or the beta B subunit, forms the FSH secretion stimulators Activin A and Activin AB respectively.

Product Details

Target Species
Human
Product Form
Purified recombinant protein - liquid
Preparation
Escherichia coli expressed recombinant inhibin beta A with N-terminal hexa-histidine tag.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
50% Glycerol
1mM EDTA
Purity
>95% by SDS PAGE/HPLC analysis
Approx. Protein Concentrations
Total protein concentration 0.13 mg/ml

Storage Information

Storage
Store at -20oC only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
6 months from date of despatch

More Information

UniProt
P08476
Entrez Gene
INHBA
GO Terms
GO:0000082 G1/S transition of mitotic cell cycle
GO:0001541 ovarian follicle development
GO:0001942 hair follicle development
GO:0002244 hemopoietic progenitor cell differentiation
GO:0006952 defense response
GO:0004871 signal transducer activity
GO:0005125 cytokine activity
GO:0005179 hormone activity
GO:0006917 induction of apoptosis
GO:0007050 cell cycle arrest
GO:0040007 growth
GO:0007166 cell surface receptor linked signaling pathway
GO:0007399 nervous system development
GO:0008083 growth factor activity
GO:0008285 negative regulation of cell proliferation
GO:0008584 male gonad development
GO:0042802 identical protein binding
GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
GO:0016563 transcription activator activity
GO:0046881 positive regulation of follicle-stimulating hormone secretion
GO:0046882 negative regulation of follicle-stimulating hormone secretion
GO:0030218 erythrocyte differentiation
GO:0030308 negative regulation of cell growth
GO:0032925 regulation of activin receptor signaling pathway
GO:0042326 negative regulation of phosphorylation
GO:0042476 odontogenesis
GO:0042541 hemoglobin biosynthetic process
GO:0042701 progesterone secretion
GO:0043509 activin A complex
GO:0043512 inhibin A complex
GO:0045077 negative regulation of interferon-gamma biosynthetic process
GO:0045578 negative regulation of B cell differentiation
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045650 negative regulation of macrophage differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048184 follistatin binding
GO:0060021 palate development
GO:0060279 positive regulation of ovulation
GO:0061029 eyelid development in camera-type eye
Regulatory
For research purposes only

Applications of Inhibin Beta A

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Western Blotting
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.