Inhibin Beta A
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Recombinant Human inhibin beta A is a single monomeric non-glycosylated polypeptide chain containing 116 amino acid fragment corresponding to residues 311-426 of the inhibin beta A (INHBA) subunit.
INHBA is a member of the transforming growth factor-beta family which, in combination with the alpha subunit, forms an inhibitor of pituitary follicle-stimulating hormone (FSH) secretion, and when combined with itself or the beta B subunit, forms the FSH secretion stimulators Activin A and Activin AB respectively.
INHBA is a member of the transforming growth factor-beta family which, in combination with the alpha subunit, forms an inhibitor of pituitary follicle-stimulating hormone (FSH) secretion, and when combined with itself or the beta B subunit, forms the FSH secretion stimulators Activin A and Activin AB respectively.
Product Details
- Target Species
- Human
- Product Form
- Purified recombinant protein - liquid
- Preparation
- Escherichia coli expressed recombinant inhibin beta A with N-terminal hexa-histidine tag.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 50% Glycerol
1mM EDTA - Purity
- >95% by SDS PAGE/HPLC analysis
- Approx. Protein Concentrations
- Total protein concentration 0.13 mg/ml
Storage Information
- Storage
- Store at -20oC only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Guarantee
- 6 months from date of despatch
More Information
- UniProt
- P08476
- Entrez Gene
- INHBA
- GO Terms
- GO:0000082 G1/S transition of mitotic cell cycle
- GO:0001541 ovarian follicle development
- GO:0001942 hair follicle development
- GO:0002244 hemopoietic progenitor cell differentiation
- GO:0006952 defense response
- GO:0004871 signal transducer activity
- GO:0005125 cytokine activity
- GO:0005179 hormone activity
- GO:0006917 induction of apoptosis
- GO:0007050 cell cycle arrest
- GO:0040007 growth
- GO:0007166 cell surface receptor linked signaling pathway
- GO:0007399 nervous system development
- GO:0008083 growth factor activity
- GO:0008285 negative regulation of cell proliferation
- GO:0008584 male gonad development
- GO:0042802 identical protein binding
- GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0016563 transcription activator activity
- GO:0046881 positive regulation of follicle-stimulating hormone secretion
- GO:0046882 negative regulation of follicle-stimulating hormone secretion
- GO:0030218 erythrocyte differentiation
- GO:0030308 negative regulation of cell growth
- GO:0032925 regulation of activin receptor signaling pathway
- GO:0042326 negative regulation of phosphorylation
- GO:0042476 odontogenesis
- GO:0042541 hemoglobin biosynthetic process
- GO:0042701 progesterone secretion
- GO:0043509 activin A complex
- GO:0043512 inhibin A complex
- GO:0045077 negative regulation of interferon-gamma biosynthetic process
- GO:0045578 negative regulation of B cell differentiation
- GO:0045648 positive regulation of erythrocyte differentiation
- GO:0045650 negative regulation of macrophage differentiation
- GO:0045944 positive regulation of transcription from RNA polymerase II promoter
- GO:0048184 follistatin binding
- GO:0060021 palate development
- GO:0060279 positive regulation of ovulation
- GO:0061029 eyelid development in camera-type eye
- Regulatory
- For research purposes only
Applications of Inhibin Beta A
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | |||
| Western Blotting |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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