- Target Species
- Product Form
- Purified protein - liquid
- Purified protein prepared from human myeloma serum by ion exchange chromatography, gel filtration and protein A chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- Please see label for expiry date.
- P01834 Related reagents
- P01857 Related reagents
- Entrez Gene
- IGKC Related reagents
- IGHG1 Related reagents
- GO Terms
- GO:0005515 protein binding
- GO:0003823 antigen binding
- GO:0005576 extracellular region
- GO:0006958 complement activation, classical pathway
- GO:0045087 innate immune response
- GO:0005624 membrane fraction
- GO:0006955 immune response
- For research purposes only
Applications of IgG1
|Application Name||Verified||Min Dilution||Max Dilution|
|Functional Assays 1|
- 1This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays. Dialysis cassette (EQU003) is suitable for this purpose.
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2018 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for IgG1
Campbell, S. et al. (2006) Proinflammatory effects of TWEAK/Fn14 interactions in glomerular mesangial cells.
J Immunol. 176:1889-98.
Hershkovitz, O. et al. (2009) NKp44 receptor mediates interaction of the envelope glycoproteins from the West Nile and dengue viruses with NK cells.
J Immunol. 183: 2610-21.
Rosano, J.M. et al. (2009) A physiologically realistic in vitro model of microvascular networks.
Biomed Microdevices. 11 (5): 1051-7.
Arnon, T.I. et al. (2008) Harnessing soluble NK cell killer receptors for the generation of novel cancer immune therapy.
PLoS One. 3(5): e2150.
Ostrowitzki, S. et al. (2012) Mechanism of amyloid removal in patients with Alzheimer disease treated with gantenerumab.
Arch Neurol. 69 (2): 198-207.
Rosental, B. et al. (2011) Proliferating Cell Nuclear Antigen Is a Novel Inhibitory Ligand for the Natural Cytotoxicity Receptor NKp44.
J Immunol. 187: 5693-702.
Bloem, K. et al. (2013) DCIR interacts with ligands from both endogenous and pathogenic origin.
Immunol Lett. pii: S0165-2478(13)00174-0.