IGFBP-7

Recombinant Human IGFBP-7
- Product Type
- Recombinant Protein
- Specificity
- IGFBP-7
IGFBP-7 (insulin-like growth factor binding protein-7) is a secreted protein which belongs to a family of IGF-BPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II. IGFBP-7 is expressed in many tumour types and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation. |
- Target Species
- Human
- Product Form
- Purified recombinant protein - lyophilized
- Reconstitution
- Reconstitute with 0.25 ml distilled water.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution. For extended storage the additiona of 0.1% BSA is recommended. - Preparation
- Purified recombinant IGFBP-7 expressed in E.coli.
- Source
- E.coli
- Buffer Solution
- 10mM Sodium Phosphate, pH6.8
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Purity
- >98% by SDS PAGE and HPLC analysis.
- Approx. Protein Concentrations
- 0.1 mg/ml after reconstitution
- Protein Molecular Weight
- 26.4 kDa (257 amino acid residues).
- Endotoxin Level
- <1EU/ug
- Regulatory
- For research purposes only
- Guarantee
- Guaranteed for 3 months from the date of reconstitution or until the date of expiry, whichever comes first. Please see label for expiry date.
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | ![]() |
0.2 | 0.4ng/well |
Western Blotting | ![]() |
1.5 | 3.0ng/lane |
- Synonyms
- Insulin-Like Growth Factor Binding PROTEIN-7
- UniProt
- Q16270
- Entrez Gene
- IGFBP7
- GO Terms
- GO:0001558 regulation of cell growth
- GO:0007155 cell adhesion
- GO:0005520 insulin-like growth factor binding
- GO:0005615 extracellular space
- GO:0008285 negative regulation of cell proliferation
PHP178

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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