Haptoglobin (Hp) is a blood plasma protein that forms high affinity complexes with free haemoglobin that is released from erythrocytes. In haemolytic anaemia, haptoglobin levels decrease as high levels of haemoglobin are released from the lysed erythrocytes.
- Target Species
- Product Form
- Purified protein from human plasma - lyophilised
- Reconstitute with sterile PBS (0.15M NaCl).
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Preservative Stabilisers
- None present
- >95% by SDS PAGE
- Store at -70oC.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
- Shelf Life
- 12 months from date of reconstitution.
- P00738 Related reagents
- Entrez Gene
- HP Related reagents
- GO Terms
- GO:0006952 defense response
- GO:0004252 serine-type endopeptidase activity
- GO:0005576 extracellular region
- GO:0006508 proteolysis
- GO:0006879 cellular iron ion homeostasis
- GO:0010942 positive regulation of cell death
- GO:0030492 hemoglobin binding
- GO:0051354 negative regulation of oxidoreductase activity
- GO:2000296 negative regulation of hydrogen peroxide catabolic process
- For research purposes only
Applications of Haptoglobin
|Application Name||Verified||Min Dilution||Max Dilution|
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Copyright © 2018 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for Haptoglobin
Mao, L. et al. (2008) MALDI-TOF/TOF-MS reveals elevated serum haptoglobin and amyloid A in Behcet's disease.
J Proteome Res. 7:4500-7.