Haptoglobin (Hp) is a blood plasma protein that forms high affinity complexes with free hemoglobin that is released from erythrocytes. In hemolytic anaemia, haptoglobin levels decrease as high levels of hemoglobin are released from the lysed erythrocytes.
- Target Species
- Product Form
- Purified protein from human plasma - lyophilized
- Reconstitute with sterile PBS (0.15M NaCl). Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Preservative Stabilisers
- None present
- >95% by SDS PAGE
- Store at -70oC.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
serine-type endopeptidase activity
cellular iron ion homeostasis
positive regulation of cell death
negative regulation of oxidoreductase activity
negative regulation of hydrogen peroxide catabolic process
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Haptoglobin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for Haptoglobin
Mao, L. et al. (2008) MALDI-TOF/TOF-MS reveals elevated serum haptoglobin and amyloid A in Behcet's disease.
J Proteome Res. 7:4500-7.