Haptoglobin

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Native Human Haptoglobin

Product Type
Purified Protein
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
PHP278 E 1 mg
Haptoglobin (Hp) is a blood plasma protein that forms high affinity complexes with free haemoglobin that is released from erythrocytes. In haemolytic anaemia, haptoglobin levels decrease as high levels of haemoglobin are released from the lysed erythrocytes.

Product Details

Target Species
Human
Product Form
Purified protein from human plasma - lyophilised
Reconstitution
Reconstitute with sterile PBS (0.15M NaCl).
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
Preservative Stabilisers
None present
Purity
>95% by SDS PAGE

Storage Information

Storage
Store at -70oC.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
Shelf Life
12 months from date of reconstitution.

More Information

UniProt
P00738 Related reagents
Entrez Gene
HP Related reagents
GO Terms
GO:0006952 defense response
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0006508 proteolysis
GO:0006879 cellular iron ion homeostasis
GO:0010942 positive regulation of cell death
GO:0030492 hemoglobin binding
GO:0051354 negative regulation of oxidoreductase activity
GO:2000296 negative regulation of hydrogen peroxide catabolic process
Regulatory
For research purposes only

Applications of Haptoglobin

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Product Specific References

References for Haptoglobin

  1. Mao, L. et al. (2008) MALDI-TOF/TOF-MS reveals elevated serum haptoglobin and amyloid A in Behcet's disease.
    J Proteome Res. 7:4500-7.