Bradykinin

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Synthetic Human Bradykinin

Product Type
Purified Protein
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
1500-0059 E 1 mg
Synthetic Human Bradykinin is a 9 amino acid peptide that acts as a vasodilator in inflammatory responses. Bradykinin is produced through cleavage of High-Molecular-Weight Kininogen (HMWK) by the protease Kallikrein and can be degraded by aminopeptidase P (APP), carboxypeptidase N (CPN) and Angiotensin-converting enzyme (ACE). Peptide sequence: RPPGFSPFR

Product Details

Target Species
Human
Product Form
Purified synthetic peptide - liquid
Preparation
Solid phase synthesis
Buffer Solution
Acetate salt
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Purity
HPLC: >99%
Approx. Protein Concentrations
1.0mg/ml
Molecular Weight
1060 Da

Storage Information

Storage
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
Shelf Life
18 months from date of despatch.

More Information

UniProt
P01042 Related reagents
Entrez Gene
KNG1 Related reagents
GO Terms
GO:0005886 plasma membrane
GO:0002576 platelet degranulation
GO:0005102 receptor binding
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0005615 extracellular space
GO:0006939 smooth muscle contraction
GO:0006954 inflammatory response
GO:0007162 negative regulation of cell adhesion
GO:0007204 elevation of cytosolic calcium ion concentration
GO:0007597 blood coagulation, intrinsic pathway
GO:0008201 heparin binding
GO:0008270 zinc ion binding
GO:0030146 diuresis
GO:0030147 natriuresis
GO:0030168 platelet activation
GO:0030195 negative regulation of blood coagulation
GO:0031093 platelet alpha granule lumen
GO:0042311 vasodilation
GO:0043065 positive regulation of apoptosis
Regulatory
For research purposes only

Applications of Bradykinin

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.