Serum Amyloid A
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Recombinant Dog serum amyloid A (SAA) is a 121 aa recombinant protein produced in a eukaryotic expression system, which includes a proprietary tag at the N-terminus.
Serum amyloid A proteins are a family of acute phase proteins, produced primarily by the liver, highly conserved in vertebrate species, and used as markers of inflammation.
Canine SAA, as with SAA in other species, is present in different isoforms, this recombinant protein corresponds to isoform 1 (SAA1). Canine SAA is composed of 111 amino acids and differs from human SAA by having an 8 aa sequence insert in the central region of the sequence.
With similar biochemical properties to the native canine SAA, this reagent may be used as a standard in immunoassays for dog serum amyloid A.
Serum amyloid A proteins are a family of acute phase proteins, produced primarily by the liver, highly conserved in vertebrate species, and used as markers of inflammation.
Canine SAA, as with SAA in other species, is present in different isoforms, this recombinant protein corresponds to isoform 1 (SAA1). Canine SAA is composed of 111 amino acids and differs from human SAA by having an 8 aa sequence insert in the central region of the sequence.
With similar biochemical properties to the native canine SAA, this reagent may be used as a standard in immunoassays for dog serum amyloid A.
Product Details
- Target Species
- Dog
- Product Form
- Purified recombinant protein - lyophilized
- Reconstitution
- Reconstitute with 1.0 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Preparation
- Purified by affinity and reversed-phase chromatography
- Buffer Solution
- 0.01M HCl
- Preservative Stabilisers
- None present
- Purity
- >95%
- Approx. Protein Concentrations
- 0.1 mg/ml after reconstitution
- Protein Molecular Weight
- 13.8 kDa
Storage Information
- Storage
- Prior to reconstitution store at -20oC.
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. - Guarantee
- 6 months from date of despatch
More Information
- UniProt
- P19708 Related reagents
- GO Terms
- GO:0006953 acute-phase response
- GO:0034364 high-density lipoprotein particle
- Regulatory
- For research purposes only
Applications of Serum Amyloid A
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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