Browsing Modes for Business Users

SOX2 antibody

Rabbit anti SOX2

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
SOX2

Product Code Applications Pack Size List Price Your Price Qty
VPA00238
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
List Price Your Price
loader

Rabbit anti Human SOX2 antibody recognizes the transcription factor SOX2, also known as SRY-related HMG-box gene 2.

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. SOX2 is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in the SOX2 gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. SOX2 lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT) (provided by RefSeq, Jul 2008).

Rabbit anti Human SOX2 antibody detects a band of 35 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti SOX2 detects a band of approximately 35 kDa in NTERA-2 cell lysates.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (H/L):HRP

UniProt
P48431
Entrez Gene
SOX2
GO Terms
GO:0005515 protein binding
GO:0001649 osteoblast differentiation
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005829 cytosol
GO:0005667 transcription factor complex
GO:0006325 chromatin organization
GO:0007050 cell cycle arrest
GO:0009611 response to wounding
GO:0010843 promoter binding
GO:0021781 glial cell fate commitment
GO:0035019 somatic stem cell maintenance
GO:0035198 miRNA binding
GO:0043281 regulation of caspase activity
GO:0043410 positive regulation of MAPKKK cascade
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050680 negative regulation of epithelial cell proliferation
GO:0070848 response to growth factor stimulus
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway

VPA00238

151204

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products
Please note