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Cyclophilin A antibody | AB03/1C10

Mouse anti Cyclophilin A

Product Type
PrecisionAb Monoclonal
Clone
AB03/1C10
Isotype
IgG1
Format
Purified
Specificity
Cyclophilin A

Product Code Applications Pack Size List Price Your Price Qty
VMA00535
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
F WB 100 µl loader
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loader

Mouse anti Human cyclophilin A antibody recognizes the Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, cyclosporin A-binding protein, CYPA or rotamase A.

The PPIA gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported (provided by RefSeq, Jul 2008).

Mouse anti Human cyclophilin A antibody detects a band of 18 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti cyclophilin A detects a band of approximately 18 kDa in HeLa cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from ascites.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
E. coli-derived recombinant human cyclophilin A (amino acids 1 - 165)
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Goat anti Mouse IgG (H/L):HRP STAR207P WB 2 ml loader
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Description Goat anti Mouse IgG (H/L):HRP

UniProt
P62937
Entrez Gene
PPIA
GO Terms
GO:0051082 unfolded protein binding
GO:0002576 platelet degranulation
GO:0006457 protein folding
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0005634 nucleus
GO:0006278 RNA-dependent DNA replication
GO:0019047 provirus integration
GO:0019061 uncoating of virus
GO:0030168 platelet activation
GO:0030260 entry into host cell
GO:0042277 peptide binding
GO:0045069 regulation of viral genome replication
GO:0046790 virion binding
GO:0050900 leukocyte migration

VMA00535

170420

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