ELAVL1 antibody | 224CT6.5.3
KO Validated
Mouse anti ELAVL1
- Product Type
- PrecisionAb Monoclonal
- Clone
- 224CT6.5.3
- Isotype
- IgG1
- Format
- Purified
- Specificity
- ELAVL1
Antibody Quality and Performance Guarantee
| Mouse anti Human ELAVL1 antibody recognizes ELAVL1, also known as ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), ELAV-like protein 1, Hu antigen R, embryonic lethal and abnormal vision, drosophila, homolog-like 1, hu-antigen R. The protein encoded by ELAVL1 gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. ELAVL1 has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy (provided by RefSeq, Sep 2012). Mouse anti Human ELAVL1 antibody detects a band of 36 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
|
- Target Species
- Human
- Western Blotting
- Anti ELAVL1 detects a band of approximately 36 kDa in HEK293 cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- Recombinant ELAVL1 protein
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml.
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- Q15717
- Entrez Gene
- ELAVL1
- GO Terms
- GO:0000166 nucleotide binding
- GO:0003729 mRNA binding
- GO:0005737 cytoplasm
- GO:0005654 nucleoplasm
- GO:0007275 multicellular organismal development
- GO:0042802 identical protein binding
- GO:0070935 3'-UTR-mediated mRNA stabilization
VMA00354
160415
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