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Kappa Light Chain antibody

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Anti Human Kappa Light Chain Antibody thumbnail image 1 Anti Human Kappa Light Chain Antibody thumbnail image 2
Anti Human Kappa Light Chain Antibody gallery image 1
Published customer image:
Horseradish peroxidase conjugated Goat anti Human kappa light chain antibody (STAR127P) used to evaluate Vedolizumab levels in serum by ELISA.
Image caption:
Vedolizumab discontinuation trough levels in association with response to subsequent all non-surgical therapy (a) and anti-TNF therapy (b) at 6 and 12 months post discontinuation. Data presented as median and IQR. TNF—Tumor necrosis factor.

From: Levartovsky A, Cohen I, Abitbol CM, Yavzori M, Fudim E, Picard O, Kopylov U, Ben-Horin S, Ungar B.
Do Vedolizumab trough Levels Predict the Outcome of Subsequent Therapy in Inflammatory Bowel Disease?
Biomedicines. 2023 May 26;11(6):1553.
doi: 10.3390/biomedicines11061553. .
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Anti Human Kappa Light Chain Antibody gallery image 2
Published customer image:
Goat anti Human Kappa Light Chain antibody (STAR127P) used as a detection reagent in an ELISA for the evaluation of vedolizumab levels in patient sera.
Image caption:
Association between vedolizumab serum drug levels and the reporting of adverse events (AEs). (a) Association between vedolizumab levels and reporting of at least one AE. (b) Association between vedolizumab levels and reporting of at least one AE, excluding fatigue and abdominal pain. (c) Association between vedolizumab trough levels of below or above 18 µg/mL and reporting of at least one AE. Abbreviations: AE = adverse event; and TL = trough level.

From: Veisman I, Barzilay O, Bruckmayer L, Haj-Natour O, Kopylov U, Eliakim R, Ben-Horin S, Ungar B.
Association of Infliximab and Vedolizumab Trough Levels with Reported Rates of Adverse Events: A Cross-Sectional Study.
J Clin Med. 2021 Sep 20;10(18):4265.
doi: 10.3390/jcm10184265.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.

Goat anti Human Kappa Light Chain:HRP

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Kappa Light Chain

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Product Code Applications Pack Size List Price Your Price Qty
STAR127P
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
C E P WB 1 ml loader
List Price Your Price
loader

Goat anti Human Kappa Light Chain antibody recognizes human kappa light chains. This antibody has been cross absorbed against pooled human myeloma proteins with lambda light chains.

Target Species
Human
Product Form
Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
Antiserum Preparation
Antisera to human kappa chains were raised by repeated immunisation of goats with purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.01% Thiomersal
50% Glycerol
Immunogen
Human kappa light chain
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/4000 1/8000
Immunohistology - Frozen
Immunohistology - Paraffin
Western Blotting
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
AbGUARD® HRP Stabilizer Plus BUF052A C E P WB 100 ml
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Description AbGUARD® HRP Stabilizer Plus
AbGUARD® HRP Stabilizer Plus BUF052B C E P WB 500 ml
List Price Your Price
Description AbGUARD® HRP Stabilizer Plus
AbGUARD® HRP Stabilizer Plus BUF052C C E P WB 1000 ml
List Price Your Price
Description AbGUARD® HRP Stabilizer Plus
TMB Signal+ BUF054A E 100 ml
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Description TMB Signal+
TMB Core BUF056A E 100 ml
List Price Your Price
Description TMB Core
TMB Core+ BUF062A E 100 ml
List Price Your Price
Description TMB Core+

References for Kappa Light Chain antibody

  1. Veisman, I. et al. (2021) Association of Infliximab and Vedolizumab Trough Levels with Reported Rates of Adverse Events: A Cross-Sectional Study.
    J Clin Med. 10 (18): 4265.
  2. Ungar, B. et al. (2021) Dose optimisation for Loss of Response to Vedolizumab- Pharmacokinetics and Immune Mechanisms.
    J Crohns Colitis. 15 (10): 1707-19.
  3. Levartovsky, A. et al. (2023) Do Vedolizumab trough Levels Predict the Outcome of Subsequent Therapy in Inflammatory Bowel Disease?
    Biomedicines. 11 (6): 1553.

RRID
AB_1102710
UniProt
P01834
Entrez Gene
IGKC
GO Terms
GO:0005515 protein binding
GO:0003823 antigen binding
GO:0005576 extracellular region
GO:0006958 complement activation, classical pathway
GO:0045087 innate immune response

STAR127P

157374 161517 165337 180601

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

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