SFRP1

Prior to reconstitution store at -20^oC.
After reconstitution store at -20^oC.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Functional Assays

Synonyms

sFrizzled Related Protein-1

UniProt

Q8N474

Entrez Gene

SFRP1

GO Terms

GO:0005886 plasma membrane

GO:0004197 cysteine-type endopeptidase activity

GO:0001649 osteoblast differentiation

GO:0001654 eye development

GO:0001657 ureteric bud development

GO:0001843 neural tube closure

GO:0001944 vasculature development

GO:0002244 hemopoietic progenitor cell differentiation

GO:0005829 cytosol

View More GO Terms

GO:0042813 Wnt receptor activity

GO:0005109 frizzled binding

GO:0005578 proteinaceous extracellular matrix

GO:0005615 extracellular space

GO:0006309 DNA fragmentation involved in apoptotic nuclear change

GO:0007420 brain development

GO:0008144 drug binding

GO:0008201 heparin binding

GO:0061133 endopeptidase activator activity

GO:0008584 male gonad development

GO:0008585 female gonad development

GO:0042802 identical protein binding

GO:0009267 cellular response to starvation

GO:0042493 response to drug

GO:0009950 dorsal/ventral axis specification

GO:0009986 cell surface

GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter

GO:0010564 regulation of cell cycle process

GO:0010719 negative regulation of epithelial to mesenchymal transition

GO:0014034 neural crest cell fate commitment

GO:0014070 response to organic cyclic compound

GO:0016563 transcription activator activity

GO:0016566 specific transcriptional repressor activity

GO:0017147 Wnt-protein binding

GO:0022601 menstrual cycle phase

GO:0030165 PDZ domain binding

GO:0030279 negative regulation of ossification

GO:0030307 positive regulation of cell growth

GO:0030308 negative regulation of cell growth

GO:0030336 negative regulation of cell migration

GO:0030514 negative regulation of BMP signaling pathway

GO:0032582 negative regulation of gene-specific transcription

GO:0032855 positive regulation of Rac GTPase activity

GO:0033689 negative regulation of osteoblast proliferation

GO:0035019 somatic stem cell maintenance

GO:0043065 positive regulation of apoptosis

GO:0043066 negative regulation of apoptosis

GO:0043193 positive regulation of gene-specific transcription

GO:0043508 negative regulation of JUN kinase activity

GO:0044344 cellular response to fibroblast growth factor stimulus

GO:0045578 negative regulation of B cell differentiation

GO:0045600 positive regulation of fat cell differentiation

GO:0045668 negative regulation of osteoblast differentiation

GO:0045671 negative regulation of osteoclast differentiation

GO:0045765 regulation of angiogenesis

GO:0045880 positive regulation of smoothened signaling pathway

GO:0046676 negative regulation of insulin secretion

GO:0046851 negative regulation of bone remodeling

GO:0048147 negative regulation of fibroblast proliferation

GO:0048546 digestive tract morphogenesis

GO:0050679 positive regulation of epithelial cell proliferation

GO:0050680 negative regulation of epithelial cell proliferation

GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation

GO:0051496 positive regulation of stress fiber assembly

GO:0051894 positive regulation of focal adhesion assembly

GO:0060070 canonical Wnt receptor signaling pathway

GO:0060071 Wnt receptor signaling pathway, planar cell polarity pathway

GO:0060218 hemopoietic stem cell differentiation

GO:0060346 bone trabecula formation

GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis

GO:0060687 regulation of branching involved in prostate gland morphogenesis

GO:0060766 negative regulation of androgen receptor signaling pathway

GO:0071305 cellular response to vitamin D

GO:0071347 cellular response to interleukin-1

GO:0071356 cellular response to tumor necrosis factor

GO:0071380 cellular response to prostaglandin E stimulus

GO:0071392 cellular response to estradiol stimulus

GO:0071456 cellular response to hypoxia

GO:0071504 cellular response to heparin

GO:0071560 cellular response to transforming growth factor beta stimulus

GO:0071773 cellular response to BMP stimulus

GO:0090246 convergent extension involved in somitogenesis

GO:0090263 positive regulation of canonical Wnt receptor signaling pathway

GO:2000052 positive regulation of non-canonical Wnt receptor signaling pathway

GO:2000054 negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification

GO:2000080 negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation

GO:2000117 negative regulation of cysteine-type endopeptidase activity

PHP253

154099 164844

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