CD1 antibody | 76-7-4
Mouse anti Pig CD1:RPE
- Product Type
- Monoclonal Antibody
- Clone
- 76-7-4
- Isotype
- IgG2a
- Specificity
- CD1
Mouse anti Pig CD1 antibody, clone 76-7-4 recognizes a porcine homologue of the human CD1 cell surface receptor. CD1 is a member of the immunoglobulin superfamily. While it is structurally similar to the MHC class I receptor CD1 differs functionally by presenting lipid antigens to T cells (Germain & Margulies, 1993). To date, five classes of the CD1 genes have been identified across different mammalian species, namely CD1A, CD1B, CD1C, CD1D, and CD1E (Brigl & Brenner, 2004). In swine various tissues express CD1C even though its gene has been reported to carry a loss-of-function mutation (Eguchi-Ogawa et al. 2007). CD1 is predominantly found on dendritic cells, macrophages, monocytes, and thymocytes (Chun et al. 1999). |
- Target Species
- Pig
- Product Form
- Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid
- Preparation
- Purified IgG prepared by combination of precipitation and chromatography techniques
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
Stabilizing agent (sucrose) - Immunogen
- Fresh dd miniature swine thymocytes
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Max Ex/Em
-
Fluorophore Excitation Max (nm) Emission Max (nm) RPE 488nm laser 496 578 RPE 561nm laser 546 578 - Regulatory
- For research purposes only
- Guarantee
- Guaranteed for 12 months from the date of despatch or until the date of expiry, whichever comes first. Please see label for expiry date.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | Neat | 1/5 |
- Flow Cytometry
- Use 10ul of the suggested working dilution to label 1x106 cells in 100ul
How to Use the Spectraviewer
Watch the Tool Tutorial Video ▸- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra
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Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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Mouse anti Pig CD45RA:FITC | MCA1751F | F | 0.1 mg | Log in | |||
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Description | Mouse anti Pig CD45RA:FITC |
Source Reference
-
Pescovitz, M.D. et al. (1984) Preparation and characterization of monoclonal antibodies reactive with porcine PBL.
J Immunol. 133 (1): 368-75.
References for CD1 antibody
-
Pauly, T. et al. (1998) Infection with classical swine fever virus: effects on phenotype and immune responsiveness of porcine T lymphocytes.
J Gen Virol. 79 ( Pt 1): 31-40.
- UniProt
- Q9XS72
- Entrez Gene
- CD1.1
- GO Terms
- GO:0005886 plasma membrane
- GO:0016021 integral to membrane
- GO:0006955 immune response
- GO:0010008 endosome membrane
- GO:0019882 antigen processing and presentation
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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