CD24 antibody | SN3
Mouse anti Human CD24:Low Endotoxin
- Product Type
- Monoclonal Antibody
- Clone
- SN3
- Isotype
- IgG1
- Specificity
- CD24
Mouse anti Human CD24 antibody, clone SN3 recognizes the human CD24 cell surface antigen, a heavily glycosylated molecule of ~35-45 kDa. CD24 is expressed by granulocytes and B lymphocytes, and by some activated T cells and T cell malignancies. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Chimpanzee - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Immunogen
- Glycoproteins purified from human NALM-1 cell line
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Endotoxin Level
- <0.01EU/μg
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of a mouse myeloma cell line
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Flow Cytometry | |||
Immunohistology - Frozen 1 | |||
Immunohistology - Paraffin |
- 1The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Bio-Rad recommends the use of acetone fixation for frozen sections.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells or cells or 100μl whole blood
- Histology Positive Control Tissue
- Tonsil
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Mouse IgG1 Negative Control:Low Endotoxin | MCA928EL | C F | 0.5 mg | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Mouse IgG1 Negative Control:Low Endotoxin |
Source Reference
-
Barcos, M. et al. (1986) Follicular mantle zone cell subpopulations detected by monoclonal antibody SN3.
Hematol Oncol. 4 (4): 251-9.
References for CD24 antibody
-
Fukukawa, T. et al. (1986) New monoclonal antibodies SN3, SN3a, and SN3b directed to sialic acid of glycoprotein on human non-T leukemia cells.
Exp Hematol. 14 (9): 850-5. -
Ohyama, M. et al. (2006) Characterization and isolation of stem cell-enriched human hair follicle bulge cells.
J Clin Invest. 116:249-60. -
Kap, Y.S. et al. (2009) A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.
J Histochem Cytochem. 57 (12): 1159-67. -
Sallustio, F. et al. (2010) TLR2 plays a role in the activation of human resident renal stem/progenitor cells.
FASEB J. 24 (2): 514-25. -
Kanderová, V. et al. (2010) Aberrantly expressed CEACAM6 is involved in the signaling leading to apoptosis of acute lymphoblastic leukemia cells.
Exp Hematol. 38: 653-660.e1. -
Franz, C. et al. (2016) Extracellular vesicles in human follicular fluid do not promote coagulation.
Reprod Biomed Online. 33 (5): 652-5.
- RRID
- AB_2275511
- UniProt
- P25063
- Entrez Gene
- CD24
- GO Terms
- GO:0005886 plasma membrane
- GO:0001666 response to hypoxia
- GO:0001775 cell activation
- GO:0001959 regulation of cytokine-mediated signaling pathway
- GO:0002237 response to molecule of bacterial origin
- GO:0002768 immune response-regulating cell surface receptor signaling pathway
- GO:0004871 signal transducer activity
- GO:0016055 Wnt receptor signaling pathway
- GO:0007204 elevation of cytosolic calcium ion concentration
- View More GO Terms
- GO:0007411 axon guidance
- GO:0008629 induction of apoptosis by intracellular signals
- GO:0009986 cell surface
- GO:0031225 anchored to membrane
- GO:0016337 cell-cell adhesion
- GO:0016477 cell migration
- GO:0019901 protein kinase binding
- GO:0030296 protein tyrosine kinase activator activity
- GO:0030856 regulation of epithelial cell differentiation
- GO:0031295 T cell costimulation
- GO:0032597 B cell receptor transport into membrane raft
- GO:0032600 chemokine receptor transport out of membrane raft
- GO:0032913 negative regulation of transforming growth factor-beta3 production
- GO:0042104 positive regulation of activated T cell proliferation
- GO:0042632 cholesterol homeostasis
- GO:0043406 positive regulation of MAP kinase activity
- GO:0043408 regulation of MAPKKK cascade
- GO:0043627 response to estrogen stimulus
- GO:0045121 membrane raft
- GO:0045730 respiratory burst
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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