TRAF2 antibody
Rabbit anti TRAF2
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- TRAF2
Rabbit anti TRAF2 antibody recognizes TNF receptor-associated factor 2 (TRAF2) also known as E3 ubiquitin-protein ligase TRAF2. TRAF2 belongs to the TNF receptor-associated factor (TRAF) family of proteins. TRAF2 directly binds to TNF receptors and other TRAF proteins; playing a major role in TNF alpha mediated activation of MAPK8/JNK and NF-kappaB. TRAF2 forms a heterodimeric complex with TRAF1, and interacts with the IAP family members cIAP1 and cIAP2 functioning as a mediator of the anti-apoptotic signals from TNF receptors. |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to TRAF2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.05% ProClin 300
50% Glycerol - Immunogen
- Recombinant human TRAF2
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- ProClin is a trademark of The Dow Chemical Company (“Dow”) or an affiliated company of Dow.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Paraffin | 1/50 | 1/200 | |
Western Blotting | 1/500 | 1/2000 |
- Western Blotting
- Rabbit anti TRAF2 antibody detects a band of approximately 56 kDa in cell lysates under reducing conditions
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml | Log in | |||
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Description | Sheep anti Rabbit IgG:RPE |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB * | 0.5 ml | Log in | |||
List Price | Your Price | ||||||
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Description | TidyBlot Western Blot Detection Reagent:HRP |
- UniProt
- Q12933
- Entrez Gene
- TRAF2
- GO Terms
- GO:0005515 protein binding
- GO:0002726 positive regulation of T cell cytokine production
- GO:0005829 cytosol
- GO:0004842 ubiquitin-protein ligase activity
- GO:0004871 signal transducer activity
- GO:0005174 CD40 receptor binding
- GO:0006919 activation of caspase activity
- GO:0007250 activation of NF-kappaB-inducing kinase activity
- GO:0008270 zinc ion binding
- View More GO Terms
- GO:0008624 induction of apoptosis by extracellular signals
- GO:0008633 activation of pro-apoptotic gene products
- GO:0009898 internal side of plasma membrane
- GO:0032743 positive regulation of interleukin-2 production
- GO:0033209 tumor necrosis factor-mediated signaling pathway
- GO:0035631 CD40 receptor complex
- GO:0043507 positive regulation of JUN kinase activity
- GO:0043623 cellular protein complex assembly
- GO:0046625 sphingolipid binding
- GO:0050870 positive regulation of T cell activation
- GO:0051092 positive regulation of NF-kappaB transcription factor activity
- GO:0051865 protein autoubiquitination
- GO:0070207 protein homotrimerization
- GO:0070534 protein K63-linked ubiquitination
AHP2534
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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