Browsing Modes for Business Users

TRAF2 antibody

Rabbit anti TRAF2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
TRAF2

Product Code Applications Pack Size List Price Your Price Qty
AHP2534
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
P WB 50 µl loader
List Price Your Price
loader

Rabbit anti TRAF2 antibody recognizes TNF receptor-associated factor 2 (TRAF2) also known as E3 ubiquitin-protein ligase TRAF2. TRAF2 belongs to the TNF receptor-associated factor (TRAF) family of proteins.

TRAF2 directly binds to TNF receptors and other TRAF proteins; playing a major role in TNF alpha mediated activation of MAPK8/JNK and NF-kappaB. TRAF2 forms a heterodimeric complex with TRAF1, and interacts with the IAP family members cIAP1 and cIAP2 functioning as a mediator of the anti-apoptotic signals from TNF receptors.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to TRAF2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.05% ProClin 300
50% Glycerol
Immunogen
Recombinant human TRAF2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
ProClin is a trademark of The Dow Chemical Company (“Dow”) or an affiliated company of Dow.

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti TRAF2 antibody detects a band of approximately 56 kDa in cell lysates under reducing conditions

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):Biotin
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):FITC
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (Fc):HRP
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
List Price Your Price
loader
Description Goat anti Rabbit IgG (H/L):HRP
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
List Price Your Price
loader
Description Sheep anti Rabbit IgG:RPE

Description Product Code Applications Pack Size List Price Your Price Quantity
TidyBlot Western Blot Detection Reagent:HRP STAR209P WB * 0.5 ml
List Price Your Price
Description TidyBlot Western Blot Detection Reagent:HRP

UniProt
Q12933
Entrez Gene
TRAF2
GO Terms
GO:0005515 protein binding
GO:0002726 positive regulation of T cell cytokine production
GO:0005829 cytosol
GO:0004842 ubiquitin-protein ligase activity
GO:0004871 signal transducer activity
GO:0005174 CD40 receptor binding
GO:0006919 activation of caspase activity
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0008270 zinc ion binding
GO:0008624 induction of apoptosis by extracellular signals
GO:0008633 activation of pro-apoptotic gene products
GO:0009898 internal side of plasma membrane
GO:0032743 positive regulation of interleukin-2 production
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035631 CD40 receptor complex
GO:0043507 positive regulation of JUN kinase activity
GO:0043623 cellular protein complex assembly
GO:0046625 sphingolipid binding
GO:0050870 positive regulation of T cell activation
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051865 protein autoubiquitination
GO:0070207 protein homotrimerization
GO:0070534 protein K63-linked ubiquitination

AHP2534

141496

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

View more products with TRAF2 specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products
Please note