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NAK antibody

Product Code Applications Pack Size List Price Your Price Qty
AHP2499
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
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loader

Rabbit anti NAK antibody recognizes NAK also known as TBK1. NAK is involved in the NF-kB signaling pathway interacting directly with IkB kinase (IKK) complex.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse Expected from Sequence
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to NAK was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.05% ProClin 300
50% Glycerol
Immunogen
Recombinant human NAK
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
ProClin is a trademark of The Dow Chemical Company (“Dow”) or an affiliated company of Dow.

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti NAK antibody detects a band of approximately 84 kDa in cell lysates under reducing conditions

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Synonyms
TBK1
UniProt
Q9UHD2
Entrez Gene
TBK1
GO Terms
GO:0005886 plasma membrane
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0009615 response to virus
GO:0005829 cytosol
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0006468 protein phosphorylation
GO:0007249 I-kappaB kinase/NF-kappaB cascade
GO:0008063 Toll signaling pathway
GO:0010008 endosome membrane
GO:0032480 negative regulation of type I interferon production
GO:0034138 toll-like receptor 3 signaling pathway
GO:0034142 toll-like receptor 4 signaling pathway
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0044419 interspecies interaction between organisms
GO:0045087 innate immune response
GO:0051219 phosphoprotein binding

AHP2499

141464 161011

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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