FTCD antibody
Goat anti Human FTCD (N-Terminal)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- FTCD
- Region
- (N-TERMINAL)
Goat anti Human FTCD antibody detects an epitope within the N-terminal (NT) region of formiminotransferase cyclodeaminase (FTCD). FTCD is a homo-octameric bifunctional enzyme which plays important roles in coupling histidine catabolism with folate metabolism, and integrating the Golgi complex with the vimentin intermediate filament cytoskeleton. FTCD is present in all mammalian cells either free in the cytosol or tightly bound to the Golgi complex, and is most abundant in the liver. FTCD is linked to two human diseases, autoimmune hepatitis and glutamate formiminotransferase deficiency (Mao et al. 2004). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to FTCD were raised by repeated immunisations of goat with highly purified antigen. Purified IgG prepared by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
0.02% Sodium Azide (NaN3) 0.5% Bovine Serum Albumin - Immunogen
- Peptide with sequence SQLVECVPNFSEGKNQ from the N-terminus of FTCD.
- Approx. Protein Concentrations
- IgG concentration 0.5mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | 1/64000 | ||
Western Blotting | 0.03 | 0.5ug/ml |
- Western Blotting
- AHP1063 detects a band of approximately 55-60kDa in human liver lysate.
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg | Log in | |||
List Price | Your Price | ||||||
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Description | Rabbit anti Goat IgG (Fc):FITC | ||||||
Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg | Log in | |||
List Price | Your Price | ||||||
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Description | Rabbit anti Goat IgG (Fc):HRP |
References for FTCD antibody
-
Mao, Y. et al. (2004) Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer.
EMBO J. 23 (15): 2963-71. -
Renous, R. et al. (2004) Characterization of the antigenicity of the formiminotransferase-cyclodeaminase in type 2 autoimmune hepatitis.
Exp Cell Res. 292 (2): 332-41.
- RRID
- AB_808584
- UniProt
- O95954
- Entrez Gene
- FTCD
- GO Terms
- GO:0005829 cytosol
- GO:0005542 folic acid binding
- GO:0005794 Golgi apparatus
- GO:0005814 centriole
- GO:0006548 histidine catabolic process
- GO:0006760 folic acid-containing compound metabolic process
- GO:0030409 glutamate formimidoyltransferase activity
- GO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity
AHP1063
161108If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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