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alpha-Lactalbumin antibody

Sheep anti Human Lactalbumin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
alpha-Lactalbumin

Product Code Applications Pack Size List Price Your Price Qty
5602-5008
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 1 ml loader
List Price Your Price
loader

Sheep anti Human lactalbumin antibody detects human alpha-lactalbumin, a small Ca2+ binding protein, the predominant protein found in human milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase complex, with beta 1,4-galactosyltransferase forming the catalytic component. Lactose synthase catalyzes and regulates the biosynthesis of lactose in the lactating mammary gland.

A folding variant of alpha-lactalbumin called HAMLET (human alpha-lactalbumin made lethal to tumor cells), has been shown to selectively kill tumor cells and control tumor progression in vivo.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Bovine Weak
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Serum - liquid
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Immunogen
Lactalbumin from human milk.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Rabbit anti Sheep IgG (H/L):Biotin 5184-2304 C E F WB 1.5 ml loader
List Price Your Price
loader
Description Rabbit anti Sheep IgG (H/L):Biotin

References for alpha-Lactalbumin antibody

  1. Gustafsson, L. et al. (2005) HAMLET kills tumor cells by apoptosis: structure, cellular mechanisms, and therapy.
    J Nutr. 135 (5): 1299-303.

RRID
AB_618544
UniProt
P00709
Entrez Gene
LALBA
GO Terms
GO:0005509 calcium ion binding
GO:0042742 defense response to bacterium
GO:0004461 lactose synthase activity
GO:0007165 signal transduction
GO:0005615 extracellular space
GO:0005989 lactose biosynthetic process
GO:0006917 induction of apoptosis
GO:0007267 cell-cell signaling

5602-5008

150677 161588 161637

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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